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HMGB1在子宫内膜癌方面的研究进展 被引量:2

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摘要 高迁移率蛋白B1(High-mobilitygroupboxprotein-1,HMGB1)是一种非组蛋白染色体蛋白质,细胞核内的HMGB1参与核小体的构成、基因转录以及DNA修复、重组。HMGB1的过表达有抑制细胞凋亡,细胞迁移等作用,HMGB1在有转移的肿瘤及恶性肿瘤的边缘强表达。HMGB1与子宫内膜癌组织的过度增生是正向相关的,随着子宫内膜恶变程度的增加而表达增强。
出处 《中国当代医药》 2010年第36期16-16,共1页 China Modern Medicine
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二级参考文献29

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