摘要
目的:研究丙泊酚或七氟烷麻醉单肺通气早期阶段呼吸末CO2差异(ETCO2)与最低PaO2值的关联。方法:36例择期胸科手术患者被随机分成P组(给予丙泊酚维持麻醉,n=18)和S组(给予七氟烷维持麻醉,n=18)两组。在FiO2=0.9时,测量双肺通气和单肺通气后5min、15min、30min和45min的动脉血气以及单肺通气前和后5min ETCO2值。结果:单肺通气中每组最低PaO2值(x)与初始ETCO2差异(y)有显著负相关性(P组;y=-0.0203x+7.2571,r2=0.5351;S组;y=-0.0257x+7.3158,r2=0.6129)。组间比较没有显著差异。结论:本研究表明双肺通气和单肺通气早期阶段ETCO2差异与单肺通气中损害的氧合功能相关。因此在丙泊酚或七氟烷麻醉单肺通气中最低PaO2值是一个简单、方便的预测氧合功能指标。
Objective： To investigate the correlation between the lowest arterial oxygen partial pressure（PaO2） recorded in the first 45m one-lung ventilation（OLV） and the end-tidal CO2（TLV） and the early phase of OLV.Methods：Thirty-six patients scheduled for elective thoracic surgery were randomly assigned to group P（n=18,maintenance of anesthesia with propofol） and group S（n=18,maintenance of anesthesia with sevoflurane）.When FiO2=0.90 ETCO2 was recorded at 5m,15m,30m and 45m before and after OLV and TLV.We examined the relationship between the initial ETCO22 difference and the lowest PaO2 value recorded at the first 45m of OLV.Results：There was a significant negative correlation between the lowest PaO2（x） value and the initial ETCO2 difference（y） during OLV in each group（group P;y=-0.0203x＋7.2571,r2 =0.5351;group S;y=-0.0257x＋7.3158,r2=0.6129）.There were no significant differences in this correlation between the groups.Conclusion：The present study suggests that the ETCO2 difference between TLV and early OLV has a correlation with impaired oxygenation later during OLV.The lowest PaO2 value is a simple and clinically convenient predictor of oxygenation during one-lung anesthesia with either propofol or sevoflurane.
出处
《黑龙江医药科学》
2010年第6期21-22,共2页
Heilongjiang Medicine and Pharmacy
