摘要
目的:对感染性心内膜炎(IE)病原菌的分布及药敏进行分析,以合理选择抗生素治疗IE。方法:对91例感染性心内膜炎住院病人的血培养/赘生物培养及药敏试验结果进行回顾性分析。结果:血培养培养的67例IE患者中,阳性的有20例(29.9%),主要致病菌为链球菌和葡萄球菌。药敏分析结果显示链球菌对青霉素敏感;葡萄球菌对左氧氟沙星、复方新诺明、环丙沙星和万古霉素敏感,而对青霉素、苯唑西林、阿莫西林耐药。赘生物培养的44例IE患者中,阳性的有4例(9.1%)。结论:感染性心内膜炎患者病原菌以链球菌和葡萄球菌为主,需依靠血培养/赘生物培养以及其他实验手段正确选择抗生索。
Objective： To analyze the distribution and drug sensitivity of bacteria of infective endocarditis （IE）,so as to help to rationally use antibiotics. Methods：The blood/neoplasm culture and drug sensitivity tests from 91 hospitalized patients with IE were studied retrospectively in Fuwai Hospital.Results：Among 67 IE patients with blood culture. 20cases（29.9%） were positive. The main bacteria were streptococcus and staphylococcus. Drug sensitivity analysis indicated that streptococcus were sensitive to penicillin, while staphylococci were resistant to penicillin, oxacillin and amoxicillin,and sensitive to levofloxaein, cntrimoxazole, erythromycin, ciprofloxacin and vancomycin. Among 44 IE patients with vegetation culture, 4 eases（9.1%） were positive. Conclusions：Streptococcus and staphylococcus are still the dominant bacteria of IE. In order to choose antibiotics correctly, blood culture and drug sensitivity test or other experimental measures to reveal bacteria are necessary.
出处
《中国医药导刊》
2010年第11期1837-1838,共2页
Chinese Journal of Medicinal Guide
基金
"重大新药创制"重大专项:<创新药物临床研究技术平台建设>(编号:02008ZX09312-018)
关键词
感染性心内膜炎
病原菌
耐药性
Infective endocarditis
Pathogenic bacteria
Drug sensitivity
