摘要
目的:观察舒芬太尼复合丙泊酚在内镜逆行胰胆管造影术(ERCP)的麻醉效果及其对循环、呼吸功能的影响,并与芬太尼复合丙泊酚进行比较。方法:选取择期行ERCP术患者30例,ASAⅠ～Ⅱ级,随机分为舒芬太尼组(S组)和芬太尼组(F组),每组15例。麻醉诱导采用静脉注射舒芬太尼0.1μg/kg(S组)或芬太尼1.0μg/kg(F组),及丙泊酚1.5mg/kg,并持续静脉注射丙泊酚4～6mg.kg-1.h-1维持麻醉,检查结束前3min停药。观察置入内镜是否顺利、有无恶心呕吐、呛咳、躁动及其他抵抗动作,记录麻醉前、麻醉后2min、10min及检查结束时的心率(HR)、血压(BP)、脉搏血氧饱和度(SPO2)、注药后意识消失和停药后意识恢复时间,清醒后询问对检查治疗过程有无记忆。结果:两组患者均在安静、平稳状态下顺利完成操作,无恶心呕吐和呛咳,对检查治疗过程均无记忆,满意度达100%。麻醉后各时点两组患者HR均明显减慢(P<0.05),麻醉后2min两组患者BP明显降低(P<0.05),所有患者SPO2均在94%以上,各时点HR、BP、SPO2组间比较差异均无统计学意义(P均>0.05)。麻醉后意识消失时间、停药后意识恢复时间组间比较差异均无统计学意义(P均>0.05)。结论:舒芬太尼或芬太尼复合丙泊酚用于内镜逆行胰胆管造影术都能提供满意的麻醉效果。
Objective：To investigate the anesthetic efficacy of sufentanil combined with propofol intravenous infusion,and its influence on respiration and circulation system in endoscopic retrograde cholangiopancreatography（ERCP） in comparison with fentanyl.Methods：Thirty ASA Ⅰ-Ⅱ patients underwent scheduled ERCP were randomly divided into sufentanil/propofol group（S） and fentanyl/propofol group（F group） with 15 patinets in each group.Anesthesia was induced with sufentanil 0.1 μg/kg（S group） or fentanyl 1.0μg/kg（F group） combined with propofol 1.5mg/kg,and maintained with propofol 4-6mg.kg-1.h-1.Propofol would be added when necessary.Anesthesia was withdrawn 3 min before the end of the examination.HR,BP and SPO_2 were continuously monitored and recorded before anesthesia,and 2 min,10 min after anesthesia and at the end point of the examination.Time when unconscious status began,and conscious recovered were recorded.Side effects like nausea and vomiting were also recorded.Results：All patients went through examination quietly and safely.No cough,nausea,vomiting or surgical consciouness were observed.HR was significantly decreased in both two groups after anesthesia（P〈0.05）.Compared with the value before anesthesia,significant decrease in BP was observed 2 min after anesthesia（P〈0.05）.SPO_2 of all patients was above 94%.There was no significant difference between the two groups in HR,BP and SPO_2.There was no significant difference between the two groups in unconscious beginning and recovery times（P all〉0.05） respectively.Conclusions：Both sufentanil/propofol combined with propofol can produce satisfactory anesthesia in ERCP.
出处
《海南医学院学报》
CAS
2011年第1期128-130,144,共4页
Journal of Hainan Medical University
基金
海南医学院科研基金资助学报项目(0020110027)~~
关键词
舒芬太尼
芬太尼
丙泊酚
麻醉
内镜逆行胰胆管造影
Sufentanil
Fentanyl
Propofol
Anesthesia
Endoscopic retrograde cholangiopancre-atography
