摘要
目的提高对Ｐａｇｅｔ病的诊治水平。方法回顾性分析１９８７年至１９９７年收治的１９例Ｐａｇｅｔ病的临床表现及诊治方法。结果本组乳腺Ｐａｇｅｔ病６例，乳腺外１３例，其中阴茎、阴囊１１例，腹股沟处１例，肛周肛管１例。随访时间０５～１１年，平均５年４个月，随访中３例复发者，其截端切片病理检查均可见病变组织，另１例死于其他疾病。结论本病的诊断主要依靠病理检查。手术是唯一有效治疗措施，手术时病灶切除必须彻底，截端组织病理检查无病变组织才能防止术后复发。
bjective The clinical signs of Pagets disease are similar to those of chronic eczema. The two are often confused,expecially estramammary Pagets disease. Only biopsy can help to differentiate them correctly. Methods 19 patients with Pagets disease were reviewed with regard to clinical analysis and treatment from 1987 to 1997. Results Six patients had breast Pagets disease and 13 had extramammary one. The latter involved scrotum and penis in 11 patients, the groin in 1,and perianal and anal in 1. Follow up showed that 3 patients had recurrences in extramammary patients who had had positive surgical margin biopsy. One patient died of other disease.Conclusions Surgery is the first choice of treatment for Pagets disease either of breast or of extramammary regions.Negative margins must be achieved to prevent local recurrence.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1999年第7期429-431,共3页
Chinese Journal of Surgery
