摘要
心房颤动是最常见的快速心律失常之一,其发生发展机制一直未得到完整的阐述。探讨心房颤动发生发展的分子机制,寻找预防、早期诊断的生物标记和干预治疗心房颤动的靶点,已成为当今心房颤动研究的热点。随着后基因组时代的来临,蛋白质组学为复杂的心房颤动机制的研究提供了一个全新的视角。现就心房颤动的蛋白质组学研究进展作简要综述。
Atrial fibrillation is one of the most common tachyarrhythmias,however,the initiation mechanism of atrial fibrillation has not yet been discovered.At present,studies of atrial fibrillation are investigating the molecular mechanism of initiation and development and seeking biological markers for early diagnosis,prevention,and possible therapeutic targets.In the post-genome era,proteomics provides novel insights into the research of mechanism of atrial fibrillation.This review examines recent progress in the proteomic study of atrial fibrillation.
出处
《心血管病学进展》
CAS
2011年第1期111-115,共5页
Advances in Cardiovascular Diseases
关键词
蛋白质组学
心房颤动
proteomics
atrial fibrillation
