摘要不安腿综合征(restless legs syndromes,RLS)是一种常见的神经系统疾病,1685年ThomasWillis首次描述该病的临床特点,1945年Ekbom将其正式命名为不安腿综合征[1]。其主要表现为休息或安静时下肢感觉不适,尤其在夜间更加剧烈,需要或强迫性活动下肢以缓解症状。
1Ekbom K, Ulfberg J. Restless legs syndromes. J Intern Med,2009,266 : 419-.431. 被引量:1
2Allen RP, Stillman P, Myers A. Physician-diagnosed restless legs syndrome in a large sample of primary medical care patients in western Europe : prevalence and characteristics. Sleep Med ,2010,11:9-10. 被引量:1
3Allen RP, Picchietti D, Hening WA, et al. Restless legs syndrome: diag- nostic criteria, special considerations, and epidemiology. Sleep Med, 2003,4 : 101-119. 被引量:1
4Tison F, Crochard A, Leger D, et al. Epidemiology of restless legs syndrome in French adults : a nationwide survey. The INSTANT study. Neurology, 2005,65 : 239 -246. 被引量:1
5Tan EK, Seah A, See S J, et al. Restless legs syndrome in an Asian popu- lation : a study in Singapore. Mov Disord ,2001,16:577-579. 被引量:1
6Hog LB, Poewe W. Restless legs syndrome. Carrop in Neurol,2005,18: 405-410. 被引量:1
7Bonati MT, Ferini-strambi L, Aridon P, et al. Auto, somal dominant, rest- less legs syndrome maps onehromosome. Brain,2003,126:1485-1492. 被引量:1
8Therypy MJ. New paradigms in the treatment of restless legs syndrome. Neurology,2005,64:28-33. 被引量:1
9Desai AV, Cherkas LF, Spector TD, et al. Genetic influences in self- reported symptoms of obstructive sleep apnoea and restless legs : a twin study. Twin Res,2004,7:589-595. 被引量:1
10O' Keeffe ST, Gavin K, Lavan JN. Iron status and restless legs syndrome in the elderly. Age Ageing, 1994,23:200-202. 被引量:1
10Walters AS,Lebrocq C,Dhar A,et al.Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome[J].Sleep Med,2003,4(2):121-132. 被引量:1