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血浆脑钠肽水平与慢性肾脏病患者心功能关系 被引量:13

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摘要 目的探讨血浆BNP水平与慢性肾脏病(CKD)患者心功能的关系。方法选取CKD患者212例。血浆BNP浓度测定采用电化学发光法(ECLA)一次性完成,左心室舒张末内径(LVDd)、左心室收缩期内径(LVDs)及心室射血分数(LVEF)采用心脏彩色多普勒测定。结果 CKDⅠ/Ⅱ期组血浆BNP水平与健康对照组差异无统计学意义,其余各组血浆BNP水平均较健康对照组增高,差异有统计学意义(P<0.05),CKD各组之间差异有统计学意义(P<0.05)。LVEF降低组血浆BNP水平为(876.4±25.3)ng/L,显著高于LVEF正常组(289.5±12.6)ng/L,差异有统计学意义(P<0.05)。血浆BNP水平与LVEF呈负相关,与LVDd、LVDs呈正相关,与被体表面积矫正后下腔静脉宽度VCD呈正相关。结论 BNP对于诊断慢性肾功能不全患者的心脏功能具有较好的相关性。
机构地区 解放军
出处 《安徽医学》 2011年第1期61-63,共3页 Anhui Medical Journal
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二级参考文献39

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