摘要
目的:探讨60岁以上女性排尿异常糖尿病患者的尿动力学变化特点及其临床意义。方法:回顾性分析57例老年女性排尿异常糖尿病患者(69.3±7.0岁的尿动力学资料,同时选取40例排尿异常的非糖尿病患者(68.8±6.1)岁和20例正常老年女性作为对照组(68.3±4.2)岁。全部患者均行自由尿流率、压力-流率、静态尿道压力测定并比较各组间相关参数异同。结果:排尿异常的糖尿病患者38.6%(22/57)表现为逼尿肌活动低下,19.3%(11/57)逼尿肌过度活动、24.6%(14/57)膀胱出口梗阻和17.5%(10/57)尿动力学表现正常;糖尿病组与正常对照组相比,最大尿流率时逼尿肌压力、膀胱顺应性、最大膀胱容量、剩余尿量,最大尿流率等参数之间差异均有统计学意义(P<0.05);与非糖尿病排尿异常患者相比,糖尿病组最大膀胱容量显著增多(592.1±165.2)ml vs.(468.8±101.3)m1(P<0.05),其他各项尿动力学参数未见明显差异。结论:60岁以上女性糖尿病和非糖尿病排尿异常患者尿动力学表现异常同样多见,但是前者最大膀胱容量显著增多,提示膀胱敏感性降低。
Objective： To evaluation the urodynamic changes of the aged diabetic women with abnormal voi ding. Methods：A total of 57 diabetic patients aged （69.3 ＋ 7.0） y with abnormal voiding were included. Cystome- try, pressure flow and static dynamic urethral pressure study were performed according to the recommendations of International Continence Society （ICS）. Forty abnormal voiding cases aged （68.8~ 6.1） y, with no diabetes, and 20 controls （68.3＋4.2） y were included. The urodynamie parameters were compared between different groups. Results ： Detrusor underactive was found in 38.6 % （ 22/57）, detrusor overactivity in 19.3 % （ 11/57）, bladder outlet obstruction in 24. 6%（14/57） and the normal urodynamic manifestation in 17. 50% （10/57） in diabetic patients. Compared to controls, the detrusor pressure at maximum flow rate, bladder compliance, the maximum bladder capacity （MBC）, the post void residual and the maximum flow rate in diabetic patients did not show significant differences （ P 〈0.05）, but to aged abnormal voiding patients with no diabetes, the MBC showed a significant difference （592. l± 165.2 ml vs. 468.8±101.3 ml）. Conclusions： The abnormality of bladder dysfunction is same common, but the MBC increased significantly in aged diabetic compared no-diabetic women indicating urodynamic studies is valuable diagnose tool and bladder sensitivity in aged diabetic women decreased.
出处
《临床泌尿外科杂志》
北大核心
2011年第1期24-27,共4页
Journal of Clinical Urology
基金
河南省医学科技攻关计划资助项目(编号200801002)
郑州市技术研究与开发经费支持项目(编号074SGHH32262)
