摘要
目的分析武汉地区住院患儿EB病毒(EBV)感染的情况及临床特点,为明确诊断、合理治疗提供帮助。方法采用ELISA法检测住院患儿EBV衣壳抗原(VCA)抗体IgM、IgG,并按年龄将患儿分为<6个月、6个月～、1岁～、3岁～、7～15岁5个组,对结果进行统计分析。结果 14840例住院患儿EBV抗体阳性7899例,感染率为53.23%;VCAIgM阳性率为4.05%(601/14840);VCAIgG阳性率为49.18%(7298/14840)。VCAIgM阳性率以<6月组最低(0.11%);VCAIgG阳性率以7～15岁组最高(79.83%)。601例VCAIgM阳性的患儿中,以呼吸道感染最多(429例,71.4%)。结论武汉地区住院患儿EBV感染率较高,EBV感染的相关疾病以呼吸道感染为主;不同年龄组患儿间EBV感染率不同。
Objective To study the condition and clinical characteristics of Epstein Barr virus（EBV） infection in hospitalized children from Wuhan region.Methods A total of 14 840 hospitalized children were classified into five age groups：less than 6 months old,6 months to 1 year old,1 to 3 years old,3 to 7 years old and 7 to 15 years old.The antibodies IgM and IgG to EBV capsid antigen（VCA） were detected using ELISA.Results In the 14 840 hospitalized children,7 899 were positive for EBV antibodies,with an infection rate of 53.23%.The positive rate of VCA-IgM was 4.05%（601/14 840） and that of VCA-IgG was 49.18%（7 298/14 840）.The lowest positive rate of VCA-IgM（0.11%） was found in the group of less than 6 months old and the highest positive rate of VCA-IgG（79.83%） was found in the group of 7 to 15 years old.Of the 601 children with positive VCA-IgM,429（71.4%） suffered from respiratory tract infection.Conclusions EBV infection is very common in hospitalized children in Wuhan.Respiratory tract infection is a leading disease in children with positive EBV antibodies.The infection rate of EBV in different age groups is different.
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2011年第1期23-25,共3页
Chinese Journal of Contemporary Pediatrics
关键词
EB病毒
武汉地区
儿童
Epstein Barr virus
Wuhan region
Child
