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基质金属蛋白酶及其抑制物与子宫内膜异位症的研究进展 被引量:6

The Role of Matrix Metalloproteinases and Their Inhibitors in Endometriosis
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摘要 子宫内膜异位症是妇科的常见疾病,其发病机制至今未明。近年来研究发现,基质金属蛋白酶(MMPs)及其抑制物(TIMPs)在该病的发生及发展中起了重要作用,现就MMPs及其抑制物TIMPs在子宫内膜异位症中的研究进展做一综述。 Endometriosis,a disease in which endometrial tissue grows outside of the uterus usually within the pelvic cavity,is one of the most persistent and enigmatic disorders affecting reproductive health. Recent studies suggest that the altered expression of MMP and TIMP may play an important role in pathogenesis of endometriosis. This summary will present general knowledge of the MMP system relative to the pathophysiology of the endometriosis as well as address its potential value to the treatment of the disease.
作者 赵重怡
出处 《中国医药科学》 2011年第1期68-69,87,共3页 China Medicine And Pharmacy
关键词 子宫内膜异位症 基质金属蛋白酶 金属蛋白酶组织抑制物 肿瘤坏死因子-Α Endometriosis Matrix metalloproteinase Tissue inhibitors of metalloproteinase TNF-a
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  • 1许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量:1365
  • 2Takahashi C,Sheng Z,Horan TP,et al.Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the mEMsbrane-anchored glycoprotein RECK[J].Proc Natl Acad Sci USA,1998,95(22):13221-13226. 被引量:1
  • 3Asano T,Tada M,Cheng S,et al.Prognostic values ofmatrixmetal loproteinase family expression in human colorectal carcinoma[J].J Surg Res,2008,146(1):32-42. 被引量:1
  • 4Clark JC,Thomas DM,Choong PF,et al.RECK a newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer[J].Cancer Metastasis Rev,2007,26 (3):675-683. 被引量:1
  • 5Toshihiko DC,Ryuichiro D,Takatomo K,et al.RECK expression in pancreatic cancer:its correlation with lower invasiveness and better prognosis[J].Clinical Cancer Research,2003,9(5):1779-1784. 被引量:1
  • 6Rajesh Varma,Terrance Rollason,Janesh K Gupta,et al.Endometriosis and the neoplastic process[J].Reproduction,2004,127(3):293-304. 被引量:1
  • 7Oral E,Ilvan S,Tustas E,et al.Prevalence of endometriosis in malignant epithelial ovary tumours[J].European Journal of Obstetrics and Gynecology and Reproductive Biology,2003,109:97-101. 被引量:1
  • 8Asano T,TadaM,Cheng S,et al.Prognostic values ofmatrixmetal loproteinase family expression in human colorectal carcinoma[J].J Surg Res,2008,146(1):32-42. 被引量:1
  • 9Jokimaa V,Oksjoki S,Kujari H,et al.Altered expression of genes involved in the production and degradation of endometrial extracellular matrix in patients with unexplained infertility and recurrent miscarriages.Mol Hum Reprod,2002; 8 (12):1111-1116. 被引量:1
  • 10Collen A,Hanemaaijer R,Lupu F,et al.Membrane-type matrix metalloproteinase -mediated angiogenesis in a fibrincollagen matrix.Blood,2003; 101(5) :1810-1817. 被引量:1

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