摘要
以O-甲基异脲硫酸氢盐、氢氧化钠、醋酸钠、甲醇为原料合成O-甲基异脲醋酸盐,考察了原料的配比和反应时间对O-甲基异脲醋酸盐收率的影响;着重讨论了重结晶时溶剂的选择对产品收率和纯度的影响。在最佳的反应条件和重结晶条件下,产品收率可达80%,纯度≥95%,熔点范围为122～124℃(文献值为123～125℃)。
O-methyl-isourea acetate was synthesized by using O-methyl-isourea hydrogen sulphate,sodium hydroxide,sodium acetate and methanol as raw materials.The effect of the amount of raw materials,reaction time and the choice of solven of recrystallization were studied.Under the optimal conditions,the yield,and the purity of product are 85% and more than 95%,respectively.The range of melting point is 122～124 ℃（while the literature value is 123～125 ℃）.
出处
《应用化工》
CAS
CSCD
2010年第12期1894-1896,共3页
Applied Chemical Industry
