摘要
目的探讨在下呼吸道感染中检出超鞭毛虫的临床意义。方法回顾性分析32例超鞭毛虫感染患者的临床资料、胸部影像学表现、纤维支气管镜和病原学检查结果。结果 32例患者临床表现为发热27例,盗汗23例,咳嗽30例,喘息4例;19例有基础疾病;血嗜酸粒细胞增高8例;32例均在呼吸道分泌物中查见活超鞭毛虫;16例肺炎和肺脓肿患者呼吸道分泌物细菌培养8例阳性;胸部影像学以肺部多叶段渗出性斑片影或大片叶段实变影伴周围局限性模糊斑片影多见;支气管镜检查可见有管腔内急性炎症反应的表现;患者经甲硝唑治疗预后良好。结论超鞭毛虫下呼吸道感染在本地区占有一定的比率,以下呼吸道机会感染和混合感染为主。
Objective To investigate the clinical significance of hypermastigote in lower respiratory tract infections. Methods The clinical manifestations, chest imaging characteristics, fiber bronchoscope and pathogenic laboratory results were retrospec- tively analyzed for 32 patients with hypermastigote infection in lower respiratory tract. Results The symptoms included fever （27）, night sweating （23）, cough （30） and wheezing （4）. Nineteen cases had underlying diseases. Eosinophilia was identified in 8 cases. Alive hypermastigotes were found in respiratory tract secretion of all the 32 cases. Bacterial culture of respiratory tract secretion was positive in 8 out of 16 cases with pneumonia or lung abscess. Chest imaging mostly showed infiltration in several lobes and segments or a large opacity with fuzzy patches around it. Bronchoscopy showed mainly acute inflammation in the lumen of respiratory tract. Metronidazole therapy resulted in good outcomes. Conclusions A certain percentage of lower respiratory tract infections were complicated with hypermastigote in Shenzhen area, mainly as opportunistic or mixed infection.
出处
《中国感染与化疗杂志》
CAS
2011年第1期16-18,共3页
Chinese Journal of Infection and Chemotherapy
关键词
超鞭毛虫
下呼吸道感染
临床医学
hypermastigote
lower respiratory tract infection
clinical medicine
