摘要
目的:分离鉴定菊科植物地胆草的化学成分,为活性筛选提供样品。方法:用80%工业乙醇提取,硅胶柱色谱分离纯化,根据理化性质和光谱分析确定结构。结果:分得8个化合物,分别为3,4-二羟基苯甲醛(3,4-dihydroxy benzaldehyde,1),对香豆酸(p-coumaric acid,2),香草酸(vanillic acid,3),丁香酸(syringic acid,4),β-谷甾醇(β-stitosterol,5),胡萝卜苷(dau-costerol,6),2,5-二甲氧基对苯醌(2,5-dimethoxy-1,4-benzoquinone,7)和二十八烷酸(n-octacosanoic acid,8)。结论:化合物1,3,4,7,8均为首次从该植物中分离得到。
Objective ： To elucidate the constituentes from the whole plant of Elephantopus scaber and to provide samples for activity screening. Method ： The chromatography on silica gel was used and the structures were determined by IR, NMR and MS spectra analysis and physicochemical properties comparison. Result： Eight com- pounds were isolated and identified as 3,4-dihydroxy benzaldehyde （1）, p-coumaric acid （2）, vanillic acid（ 3 ）, syringic acid （ 4 ） ,β-stitosterol （ 5 ） , daucosterol （ 6 ） , 2,5 -dimethoxy-1,4-benzoquinone （ 7 ） , n-octacosanoic acid （ 8 ）. Conclusion： The compounds 1 ,3,5,7 and 8 were isolated from the plant scaber for the first time.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第3期101-103,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
地胆草
化学成分
2
5-二甲氧基对苯醌
丁香酸
Elephantopus scaber
chemical constiuents
2,5-dimethoxy-1,4-benzoquinone
syringic acid
