摘要
采用各种柱色谱法对紫红獐牙菜的石油醚和正丁醇部位进行分离纯化,从石油醚部位分离鉴定得到6个化合物,利用理化性质和波谱学方法分别鉴定为oleanolic acid(1),swerchirin(2),sweriaperenine(3),bellidifo-lin(4),gentiacaulein(5)和1,7,8-trihydroxy-3-methoxyxanthone(6);从正丁醇部位分离鉴定得到9个化合物,分别鉴定为8-[(β-D-glucopyranosyl)oxy]-1,5-dihydroxy-3-methoxyxanthone(7),5-[(β-D-glucopyranosyl)oxy]-1,8-di-hydroxy-3-methoxyxanthone(8),7-[(β-D-xylopyranosyl)oxy]-1,8-dihydroxy-3-methoxyxanthone(9),8-[(β-D-gluco-pyranosyl)oxy]-1,3,5-trimethoxyxanthone(10),swertiamarin(11),tetrahydrosertianolin(12),8-hydroxy-10-hydro-sweroside(13),campestroside(14)以及uridine(15)。其中,化合物15首次从该属植物中得到,化合物9、10、12和13首次从该植物中分离得到。
The chemical constituents of Swertia punicea Hemsl.were isolated by various column chromatographic methods.Fifteen compounds were obtained and identified as oleanolic acid（1）,swerchirin（2）,sweriaperenine（3）,bellidifolin（4）,gentiacaulein（5）,isobellidifolin（6）,8-[（β-D-glucopyranosyl）oxy]-1,5-dihydroxy-3-methoxyxanthone（7）,5-[（β-D-glucopyranosyl）oxy]-1,8-dihydroxy-3-methoxyxanthone（8）,7-[（β-D-xylopyranosyl）oxy]-1,8-dihydroxy-3-methoxyxanthone（9）,8-[（β-D-glucopyranosyl）oxy]-1,3,5-trimethoxyxanthone（10）,swertiamarin（11）,tetrahydrosertianolin（12）,8-hydroxy-10-hydrosweroside（13）,campestroside（14）,and uridine（15）.Compounds 15 were isolated from this genus and 9,10,12,13 were obtained from this plant for the first time.
出处
《天然产物研究与开发》
CAS
CSCD
2010年第6期979-983,共5页
Natural Product Research and Development
基金
国家自然科学基金(30271590)
关键词
紫红獐牙菜
石油醚部位
正丁醇部位
口山酮
烯醚萜
Swertia punicea Hemsl.
petroleum ether fraction
n-butanol fraction
xanthonoids
iridoid glycosides
