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肝细胞癌发生和发展相关的重要分子通路 被引量:1

Cellular signaling pathways involved in hepatoceilular carcinoma occurrence and progression
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摘要 广泛的流行病学研究已经阐明了导致肝细胞癌(HCC)发生的主要危险因素,这使得我们对HCC发病的认识取得了很大进步。迄今,HCC发病的分子机制仍不清楚。根据已报道的研究结果,在病毒或肝毒性化学物的作用下,肝组织内出现了异常变化,这些变化一方面引起细胞内信号传导通路的显著改变,另一方面导致细胞内基因表达出现异常,最终形成了肿瘤。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2010年第12期955-957,共3页 Chinese Journal of Hepatology
基金 基金项目:国家自然科学基金面上项目(30972906) 高等学校博士学科点专项科研基金资助项目(20070246112) 国家高技术研究发展计划(863计划)(2007AA022479)
关键词 肝细胞 信号传导 Carcinoma, hepatocellular Signal transduction
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参考文献16

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