摘要
目的探讨奥卡西平治疗癫痫的临床效果。方法选择2007年1月至2009年10月门诊或住院治疗的64例癫痫患者,随机分为治疗组和对照组各32例,治疗组用奥卡西平治疗,对照组用苯妥英钠治疗,比较两组疗效和不良反应。结果治疗组总有效率为87.5%,对照组总有效率为68.8%,两组疗效比较差异有统计学意义(P<0.05),治疗组疗效要好于对照组;治疗组患者有4例出现不良反应,不良反应发生率为12.5%,对照组有11例患者出现不良反应,不良反应发生率为34.3%,经卡方检验比较,差异有统计学意义(P<0.05),奥卡西平的不良反应少于苯妥英钠。结论奥卡西平治疗癫痫临床效果显著,值得在临床更多应用。
Objective To explore the clinical effect of oxcarbazepine to treat epilepsy.Method Select 64 epilepsy patients that treated in our hospital,who are randomly divided into treat group and control group,32 patients each group,the treat group are treated with oxcarbazepine and the control group are treated with phenytoin,compare their treat effect and adverse effect.Results The total effect of treat group is 87.5%,which of the control group is 68.8%,the difference has statistical significance（P0.05）,the treat effect of treat group is better than control group;4 patients of the treat group have adverse effect,the rate is 12.5%,11 patients of the control group have adverse effect,the rate is 34.3%,the difference is statistical significant（P0.05）.Conclusion It has good effect of using oxcarbazepine to treat epilepsy and can be widely used in clinic.
出处
《中国医药指南》
2011年第1期16-17,共2页
Guide of China Medicine
关键词
奥卡西平
癫痫
苯妥英钠
疗效
Oxcarbazepine
Epilepsy
Phenytoin
Treat effect
