摘要
目的观察血液灌流(HP)治疗急性有机磷中毒(AOPP)的疗效。方法对2008年3月-2010年3月收治的急性中重症有机磷中毒患者46例随机分为两组。其中血液灌流组24例为治疗组,常规治疗组22例为对照组。对照组给予洗胃、利尿、阿托品解毒,解磷定恢复胆碱酯酶活性等对症治疗。治疗组在常规治疗的基础上加用血液灌流治疗。比较两组疗效。结果治疗组意识恢复时间、住院天数低于对照组(P<0.05),阿托品总量明显减少(P<0.05),治愈率高于对照组(P<0.05),病死率低于对照组(P<0.05)。结论血液灌流可缩短昏迷时间,减少并发症,提高治愈率,减少医护人员工作量,缩短住院日,降低病死率,且操作简单、安全、可靠,是抢救急性中重症有机磷中毒患者有效方法之一。
Objective To observe the therapeutic effects hemoperfusion on acute organic phosphorus poisoning（AOPP）. Methods Forty four cases with severe AOPP from Mar. 2008 to Mar. 2010 were randomly assigned to receive routine treatment（ control group, n = 22, routine treatment including gastric lavage, diuresis, using atropine and pralidoxime, etc. ） or receive HP based on the routine（ experiment group, n = 24）. The curative effect was compared. Results The time of consciousness recovery and hospital days in experiment group were less than that in the control group（ P 〈 0.05 ）. The total dose of Atropine in the experiment group was significantly reduced the total（P 〈0.05 ）. The recovery rate and case fatality rate in the experiment group were lower than that in control group（P 〈 0.05 ）. Conclusion HP can shorten the coma time and the hospital days, reduce complications, increase recovery rate and decrease the case fatality rate. It is a simple, safe and effective method in rescuing of patients with AOPP.
出处
《中华全科医学》
2011年第1期62-63,共2页
Chinese Journal of General Practice
关键词
血液灌流
有机磷
中毒
Hemoperfusion
0rganophosphorus
Poisoning
