期刊文献+

血清-腹水白蛋白梯度预测门静脉高压性腹水及食管静脉曲张的界值探讨

Cutoff values for serum-ascites albumin gradient in predicting portal hypertensive ascites and esophageal varices
下载PDF
导出
摘要 目的探讨血清-腹水白蛋白梯度预测门静脉高压性腹水及食管静脉曲张的最佳诊断界值。方法回顾性分析118例因腹水住院的患者的临床资料,并应用ROC曲线分析血清-腹水白蛋白的梯度诊断门静脉高压性腹水和预测食管静脉曲张的诊断界值。结果血清-腹水白蛋白梯度诊断门静脉高压腹水的最佳诊断界值为17 g/L,敏感度为84.29%,特异度为70.37%,准确度为81.4%。当诊断界值为11 g/L时,敏感度为94.29%,特异度为44.44%,准确度为79.3%。预测食管静脉曲张的最佳诊断界值为18 g/L,敏感度为92.86%,特异度66.67%,准确度为88.24%。结论 与传统的血清-腹水白蛋白梯度界值(11g/L)相比,界值为17 g/L,预测门静脉高压性腹水具有较高的准确度。诊断界值为18g/L时,对食管静脉曲张有一定的预测价值。 ObjectiveTo explore cutoff values for serum-ascites albumin gradient on predicting portal hypertensive ascites and varices.Methods 118 cases were included in this retrospective analysis.The cutoff values for serum-ascites albumin gradient in predicting portal hypertensive ascites and esophageal varices were determined by ROC curve.ResultsThe best value was 17 g/L for serum/ascites albumin gradient on predicting portal hypertensive ascites.The diagnostic sensitivity,specificity and accuracy were 84.29%,70.37% and 81.4%,respectively.While the diagnostic sensitivity,specificity and accuracy were 94.29%,44.44% and 79.3%,with a value of 11g/L.With the best cutoff value of 18 g/L,the sensitivity,specificity and accuracy were 92.86%,66.67% and 88.24% on predicting esophageal varices.ConclusionThe serum-ascites albumin gradient has a high diagnostic accuracy with a value of 17g / L than that of 11g/L for predicting portal hypertensive ascites.With a value of 18g/L,the serum-ascites albumin gradient is valuable for predicting esophageal varices.
出处 《现代实用医学》 2010年第11期1224-1226,共3页 Modern Practical Medicine
关键词 食管和胃静脉曲张 腹水 门静脉高压 血清-腹水白蛋白梯度 Esophageal and gastric varices Ascites Portal hypertension Serum-ascites albumin gradient
  • 相关文献

参考文献8

  • 1Moore KP,Wong F,Gines P,et al.The management of ascites in cirrhosis:report on the consensus conference of the International Ascites Club[J].Hepatology,2003,38(1):258-266. 被引量:1
  • 2陈晓明,罗政仁,姒健敏.血清—腹水白蛋白梯度与门静脉高压的诊断[J].南华大学学报(医学版),2006,34(4):594-596. 被引量:2
  • 3王友春,马建党,范银忠.血清-腹水白蛋白梯度与食管静脉曲张关系的临床研究[J].临床肝胆病杂志,2006,22(1):45-46. 被引量:7
  • 4Khandwalla HE,Fasakin Y,El-Serag HB.The utility of evaluating low serum albu-min gradient ascites in patients with cirrhosis[J].Am J Gastroenterol 2009,104(6):1401-1405. 被引量:1
  • 5Demirel U,Karincaoglu M,Harputluoglu M,et al.Two findings of portal hypertension:evaluation of correlation between senull-ascites albumin gradient and esophageal varices in non-alcoholic cirrhosis[J].Turk J Gastroenterol 2003,14(4):219-222. 被引量:1
  • 6Wong CL,Holroyd-Leduc J,Thorpe KE,et al.Does this patient have bacterial peritonitis or portal hypertension? How do I perform a paracentesis and analyze the results[J] ? JAMA,2008,299(10):1166-1178. 被引量:1
  • 7Hong WD,Zhu QH,Huang ZM,et al.Predictors of esophageal varices in patients with HBV-related cirrhosis:a retrospective study[J].BMC Gastroenterol,2009,11(9):1-7. 被引量:1
  • 8Das BB,Purohit A,Acharya U,et al.Serum-ascites albumin gradient:a predictor of esophageal varices with ascites[J].Indian J Pedi atr,2001,68(6):511-514. 被引量:1

二级参考文献14

  • 1Schepis F,Cam ma C,Niceforo D,et al.Which patients with cirrhosis should undergo endoscopic screening for esophageal varices detection?[J].Hepatology,2001,33:333. 被引量:1
  • 2Das BB,Purohit A,Acharya U,et al.Serum-ascites albumin gradient:a predictor of esophageal varices with ascites[J].Indian J Pediatr,2001,69(6):511~4. 被引量:1
  • 3Mene A,Sharma D,Raina VK.Correlation between serum-ascites albumin concentration gradient with gastrointestinal bleeding in patients of portal hypertension[ J ].Trop Doct,2003,33 (1):39 ~ 41. 被引量:1
  • 4Schiff L,Schiff E.Disease of the liver[ M ].Philadelphia:JB Lippincott,1993:28. 被引量:1
  • 5孙灏珠.实用内科学(第11版)[M].北京:人民卫生出版社,2001.1850. 被引量:1
  • 6Torres E,Barros P,Calmet F.Correlation between serum-ascites albumin concentration gradient and endoscopic parameters of portal hypertension[ J].Am J Gastroenterol,1998,93 (11):2172 ~ 8. 被引量:1
  • 7Runyon BA,Montano AA,Akriviadis EA,et al.The serum-ascites.dbumin gradient is superior to the ebudate-transudate concept in the differential diagnosis of ascites[J].Ann Intern Med,1992,117(2):215-220. 被引量:1
  • 8Hoefs JC.Serum Pnlein concentration cord portal pressure[J].Determine the ascites flnid protein concetration in partients with chronic liver disease J Lab Clin Med,1983,102(2):260-273. 被引量:1
  • 9Elis A,Meisel s,Tishler T,et al.Acites fluid to serum bilrubin concentration ratio for the classification of transudates or exudates[J].Am J Gastroenterol,1998,93(3):401-403. 被引量:1
  • 10Akriviadis EA,Kapnias D,Hadjigariveal M,et al.Serum/ ascties albumin gradientl:its valne as a rational approach to the differential diagnosis of ascites[J].Scard J Gastroenterol,1996,31(3) 814-817. 被引量:1

共引文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部