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光致皮肤损伤机制研究进展及防护 被引量:16

Advance in the mechanisms and protection of ultraviolet-induced skin damage(Review)
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摘要 太阳辐射是指到达地球表面连续电磁辐射,包括部分紫外线和可见光。其中可见光波长为400nm^800nm,紫外线波长为200nm^400nm,紫外线又可分为短波紫外线、中波紫外线和长波紫外线。不同波段紫外线辐射所引起的生物学效应及皮肤疾病不相同,其中UVA引起皮肤晒黑、皮肤光敏反应及皮肤光老化,UVB则主要引起皮肤红斑及皮肤肿瘤。因此,进一步掌握光致皮肤损伤机制及正确的紫外线防护措施,对相关疾病的治疗及预防有着重要的临床指导意义。 Solar radiation reaching the Earth's surface is a continuous electromagnetic radiation,including ultraviolet and visible parts,in which visible light wavelength is 400~800nm,ultraviolet wavelength is 200 ~ 400nm.Ultraviolet can be divided into short-wave ultraviolet(UVC 200 ~ 290nm),ultraviolet B(UVB 290 ~ 320nm),and UVA(320 ~ 400nm).In the UV and visible light spectrum,the longer the wavelength,the deeper transmission;Therefore,UVB involve only the epidermis,while UVA and visible light had significant effects on the dermis.Different bands of light caused by UV radiation show different biological effects,in which UVA can cause skin tanning,skin photosensitization reaction and skin photo-aging,while UVB is the main cause of skin erythema,immune suppression and skin cancer.Therefore,how to prevent the damage of ultraviolet radiation and UV-induced skin damage has an important clinical significance.
出处 《皮肤病与性病》 2010年第4期24-27,共4页 Dermatology and Venereology
关键词 光线(紫外线) 光老化 皮肤肿瘤 预防 机制 Ultraviolet Photo-aging Skin cancers Prevention Mechanism
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