摘要
目的 :监测清晨血压变化参数与对应时域的缺血 ST段演变相关性研究 ,观察冠心病合并高血压患者血压、心率改变是否与心肌缺血改变存在相关性。 方法 :对 79例冠心病合并高血压患者 (高血压组 )以及 5 1例单纯冠心病患者 (对照组 ) ,行同步动态血压与动态心电图监测 2 4小时 ,获得的血压、心率指标和 ST段压低数据进行统计分析。 结果 :高血压组的清晨血压 (收缩压、平均脉压、舒张压 )回升与对应时域的 ST段压低呈正相关关系 (P<0 .0 5 ,r=0 .39、0 .18、0 .33) ;尤以清晨血压回升差值 (收缩压、平均脉压、舒张压 )和心肌耗氧量与对应 ST段压低的相关性更为显著 (P<0 .0 1,r=0 .38、0 .13、0 .2 9、0 .2 3) ,而对照组无明显差异。 结论 :清晨清醒前后血压升高与心肌缺血的发生呈正相关 ,且多为无痛性心肌缺血 ,尤以昼夜节律消失者为著。
Objective:To investigate the relationship between blood pressure surge and corresponding ischemic ST segment depression in coronary heart disease with hypertension patients. Methods:Seventy nine patients with coronary heart disease(CHD)and hypertension were monitored with Ambulatory blood pressure monitoring and Holter in the mean time for 24 h.The data of blood pressure and ST segment depression were calculated and analysed by a computer.The control group do the same. Results:There was a positive correlation in hypertension group between morning blood pressure surge and the corresponding ST segment depression( p <0 05, r= 0 39、0 18、0 33 respectively),especially between the difference of morning blood pressure surge myocardial oxygen consumption(MVO 2)and ST segment depression ( p <0 01, r =0 38、0 13、0 29、0 23 rspectively);and there is no difference in the control group. Conclusion:There is a positive linear correlation between morning blood pressure surge and myocardial ischemia,and the ischemic changes in most cases are silent myocardial ischemia.
出处
《中国循环杂志》
CSCD
北大核心
1999年第3期149-151,共3页
Chinese Circulation Journal
关键词
动态血压
心肌缺血
冠心病
心率变化
Ambulatory blood pressure
Myocardial ischemia
Morning blood pressure surge
