摘要
将抗氧化中药绞股蓝甙—丹参复方制剂用于治疗工业性氟中毒患者,观察其对工业性氟中毒的治疗作用。发现服用绞股蓝皂甙—丹参复方组半年患者红细胞超氧化物歧化酶(superoxidedis-mutaseSOD)含量及活性增高,血浆丙二醛(malonaldehydeMDA)含量降低,尿氟排出增多,血Ca升高,尿Ca排出增多,血尿素氮、肌酐正常。结果表明,用SOD诱导剂,氟中毒患者红细胞SOD含量及活性升高,减轻了体内氟的蓄积。
The damnification of lipid ove - oxidation exists inindustrial fluorois. After half a year's treatment by using anti- oxidation combination preparation of Danshan - Jiaogulanon the patients of industrial fluorosis. h is found tha thesuperoxide dismutase activity in red blood ecll increasedsubstantially,the fluorine content in urine increased too, themalonaldhyde(MDA) content in bllos plasma decreased, andwithout side - effect of kidney(parenchyma) demnification. Itsuggests that the medicine could be used to treat industrialfluorosis.
出处
《贵州医药》
CAS
1999年第3期165-167,共3页
Guizhou Medical Journal
关键词
工业性
氟中毒
绞股蓝皂甙
丹参复方制剂
治疗
Anti-oxidation teaditional Chinese medicine,Industrial fluorosis, Superoxide dismutase, Malonaldehyde