摘要
目的 探讨行颈动脉支架置入术（CAS）患者术前预防性应用阿托品对术中、术后发生低血压、心动过缓及心脏疾病并发症的影响.方法 南京军区南京总医院神经内科自2008年11月至2010年5月行CAS治疗颈动脉粥样硬化患者77例,其中术前预防性应用阿托品患者（预防组）42例,术前未预防性心用阿托品患者（对照组）35例.记录患者的临床资料及围手术期心血管不良事件的高危因素,比较2组患者围手术期心血管系统并发症等的发生率.结果 2组患者的临床资料及围手术期心血管不良事件的高危因素、血管形态学特点及操作要素相比较差异均无统计学意义（P＞0.05）;与对照组比较,预防组患者术中心动过缓、围手术期心动过缓、围手术期心脏疾病并发症的发生率较低,差异有统计学意义（P＜0.05）.结论 术前预防性应用阿托品能降低CAS术中、术后发生心动过缓及心脏疾病并发症的风险.
Objective To investigate the effect of prophylactic administration of atropine before carotid angioplasty and stenting （CAS） on the happening of intraoperative and postoperative hypotension,bradycardia or cardiovascular complications. Methods Seventy-seven patients with carotid atherosclerosis, admitted to our hospital from November 2008 to May 2010 and performed CAS, were chosen in the study. Prophylactic administration of atropine before CAS was performed on 42 patients and the other 35 without atropine administration were adopted as control group. The clinical data of these patients were analyzed and the high risk factors of cardiovascular events （hypotension or bradycardia） at the perioperative period were observed. The incidence of cardiovascular complications at the perioperative period was also recorded and compared. Results No significant differences on the clinical data, high risk factors of cardiovascular events and morphological characteristics of the vessels were noted between the 2 groups （P〉0.05）. The operation procedures were almost the same between the 2 groups. As compared with the control group, the atropine treatment group enjoyed significantly lower incidences of intraoperative or perioperative bradycardia and cardiovascular complications at the perioperative period （P〈0.05）. Conclusion The prophylactic administration of atropine before CAS decreases the incidence ofbradycardia and cardiovascular complications during and after CAS.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2010年第12期1250-1254,共5页
Chinese Journal of Neuromedicine
关键词
颈动脉
支架
低血压
心动过缓
阿托品
并发症
Carotid artery
Stenting
Hypotension
Bradycardia
Atropine
Complication
