摘要
目的:探讨超声引导下经阴道小卵泡穿刺术对多囊卵巢综合征(PCOS)不孕患者内分泌功能和卵巢基础窦卵泡计数的影响。方法:选择31例对克罗米芬治疗无反应的PCOS不孕患者,在超声引导下进行卵泡穿刺抽吸卵泡液,对比观察穿刺前后患者卵巢基础窦卵泡计数以及内分泌功能的变化,并观察其排卵及妊娠情况。结果:穿刺治疗后31例患者血睾酮和黄体生成素水平均显著降低,卵巢基础窦卵泡计数减少,与治疗前相比差异有统计学意义。完成卵泡穿刺治疗后连续观察6个月,共有14例患者妊娠。结论:超声引导下卵泡穿刺术能改善PCOS不孕患者的内分泌状况,减少卵巢基础窦卵泡计数,促进卵巢排卵,是治疗药物治疗无效的PCOS患者的安全有效方法。
Objective： To explore the effect of transvaginal immature follicle puncture on endocrine function and ovarian basic an- tral follicle count of infertile patients with polycystic ovary syndrome （PCOS） . Methods： 31 clomiphene resistant PCOS patients with infer- tility were selected, follicular fluids were abstracted by ultrasound - guided follicular puncture, the changes of endocrine function and ovarian basic antral follicle count before and after follicular puncture were compared and observed, the ovulatory and pregnant status were observed. Results： After follicular puncture, the levels of serum testosterone and luteinizing hormone decreased significantly, ovarian basic antral follicle count decreased, there was significantly difference before and after follicular puncture ; 14 patients became pregnancy within 6 months after treatment. Conclusion： Ultrasound - guided immature follicle puncture can improve the endocrine function of PCOS patients with infertility, reduce ovarian basic antral follicle count, promote ovulation, which is a safe and effective method in treatment of clomiphene resistant PCOS patients with infertility.
出处
《中国妇幼保健》
CAS
北大核心
2010年第33期4937-4938,共2页
Maternal and Child Health Care of China
