期刊文献+

金葡菌疫苗的研究进展 被引量:5

Progress in Research on Staphylococcus aureus Vaccine
原文传递
导出
摘要 金葡菌(Staphylococcus aureus,SA)是人体感染的常见病原菌,随着抗菌素的广泛使用,其耐药性也日趋严重,临床用药面临着严峻的挑战。20世纪60年代以来,人们不断尝试各种防治SA感染的免疫手段,到目前为止,虽尚未发现一种行之有效的免疫手段应用于临床,但在探索过程中,人们发现,免疫预防与治疗具有广阔的应用前景。本文对近年来SA疫苗的研究进展作一综述。 Staphylococcus aureus(SA)remain an important cause of infectious diseases in both the community and the clinic,and has developed resistance to multiple drugs since the wide application of antibiotics,bring a severe challenge for the clinics to combat againist the pathogen.Several approaches to prevent SA infection have undertaken since 1960s.Though there is no currently available approach in clinic,immunoprophylaxis is found to be of an excellent prospect.This paper reviews the progress in research of SA vaccine in recent years.
出处 《中国生物制品学杂志》 CAS CSCD 2010年第11期1271-1274,共4页 Chinese Journal of Biologicals
关键词 葡萄球菌 金黄色 疫苗 免疫防治 Staphylococcus aureus Vaccine Immunoprophylaxis
  • 相关文献

参考文献32

  • 1Kluytmans J, van Belkum A, Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks [J]. Clin Microbiol Rev, 1997, 10 (3): 505-520. 被引量:1
  • 2Diekema DJ, Pfaller MA, Schmitz FJ, et al. Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the sentry antimicrobial surveillance program, 1997-1999 [J]. Clin Infect Dis, 2001, 32 (Suppl 2): S114-S132. 被引量:1
  • 3Richardson AR., Libby SJ, Fang FC. A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity [J]. Science, 2008, 319 (5870): 1672-1676. 被引量:1
  • 4Schaffer AC, Lee JC. Staphylococcus aureus and immunotherapies [J]. Infect Dis Clin North Am, 2009, 23 (1): 153-171. 被引量:1
  • 5Creech CB 2nd, Gayle Johnson BG, Alsentzer AR, et al .Vaccination as infection control: a pilot study to determine the impact of Staphylococcus aureus vaccination on nasal carriage [J]. Vaccine, 2009,28 ( 1 ) : 256-260. 被引量:1
  • 6Guidry A, Fattom A, Patel A, et al. Prevalence of capsular serotypes among Staphylococcus aureus isolates from cows with mastitis in the United States [J]. Vet Microbial, 1997, 59 (1): 53-58. 被引量:1
  • 7Lee JW, O'Brien CN, Guidry AJ, et al. Effect of a trivalent vaccine against Staphylococcus aureus mastitis lymphocyte subpopula- tions, antibody production, and neutrophil phagocytosis [J]. Can J Vet Res, 2005, 69 (1): 11-18. 被引量:1
  • 8Luby CD, Middleton JR, Ma J, et al. Characterization of the antibody isotype response in serum and milk of heifers vaccinated with a Staphylococcus aureus baeterin (Lysigin)[J]. J Dairy Res, 2007, 74 (2) : 239-246. 被引量:1
  • 9Hume EB, Dajcs JJ, Moreau JM,et al. Immunization with alphatoxin toxoid protects the cornea against tissue damage during experimental Staphylococcus aureus keratitis [J]. Infect Immun, 2000, 68 (10): 6052-6055. 被引量:1
  • 10Bubeck Wardenburg J, Schneewind O. Vaccine protection against Staphylococcus aureus pneumonia [J]. J Exp Med,2008, 205 (2) : 287-294. 被引量:1

同被引文献70

  • 1邓军昌.浅谈鸡葡萄球菌病的诊断与防治[J].中国畜牧兽医文摘,2012,28(10):190-191. 被引量:2
  • 2雷延昌,桂希恩,冯国琴.金黄色葡萄球菌的耐药性及其耐氟喹诺酮机制的研究[J].中华内科杂志,2001,40(3):176-179. 被引量:17
  • 3焦新安,杨静.沙门氏菌属鞭毛蛋白共同抗原表位的初步定位[J].中华微生物学和免疫学杂志,1993,13(6):351-354. 被引量:10
  • 4高艳利,杨思文,樊凯奇,陈静,王娟.SDS-PAGE电泳技术分析蛋白质的研究[J].辽宁化工,2007,36(7):460-463. 被引量:40
  • 5Daniel A, Euler C, Collin M, et al. Synergism between a novel chimeric lysin and oxacillin protects against infection by methicillin resistant Staphylococcus aureus[J].Antimicrob Agents Chemother, 2010,54(4): 1603-1612. 被引量:1
  • 6Glowalla E, Tosetti B, Krenke M, et al. Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus[J].Infect Immun,2009,77(7):2719- 2729. 被引量:1
  • 7Ragle B E, Bubeck Wardenburg J. Anti-alpha-hemolysin monoclonal antibodies mediate protection against Staphylococcus aureus pneumonia[J].Infect Immun,2009,77(7):2712-2718. 被引量:1
  • 8Sorensen A L, Nagai S, Houcn G, et al. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis[J]. Infect Immun,1995,63(5):1710- 1717. 被引量:1
  • 9Burts M L, Williams W A, DeBord K, et al. EsxA and EsxB are secreted by an ESAT- 6- like system that is required for the pathogenesis of Staphylococcus aureus infections[J].Proc Nail Acad Sci USA,2005,102(4): 1169-1174. 被引量:1
  • 10Bagnoli F, Fontana M R, Soldaini E, et al. Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus[J].Proc Natl Acad Sci USA,2015,112(12):3680-3685. 被引量:1

引证文献5

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部