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急性脑梗死病人血浆内NO浓度变化及其意义

The nitric oxide change and its significance in the blood plasma of patients with acute brain infarction
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摘要 目的 探讨脑梗死急性期及恢复期病人血浆内NO浓度变化的临床意义。方法 对40例急性期脑梗死病人进行了急性期与恢复期血浆内NO、cGMP及SOD浓度的测定观察分析。结果 急性期NO(5.05±0.40μmo/L)浓度明显高于恢复期(2.81±0.39μmol/L),同时cGMP、SOD亦有相应动态改变。结论 NO在缺血性脑损伤中具有重要的临床意义。 Objective To investigate the change of NO concentration and its significance in the blood plasma of patients with acute brain infarction. Methods The concentration of NO cGMP and SOD in blood plasma of 40 patients with acute brain infarction wes examined and analyzed in acute period and convalescence. Results The concentration of NO in acute period (5. 05+0. 40umol/L) was higher than convalescence (2. 81+0. 39umol/L), and the concentratcon of cGMP and SOD had also the corresponding changes in blood plasma. Conclusion The changes of NO concentration in acute period suggested it might implicate the brain injury.
出处 《实用心脑肺血管病杂志》 1999年第1期12-13,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 NO SOD 脑梗死 临床意义 Nitric oxide (NO) cGMP SOD Brain infarctisn
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