摘要
目的:比较帕罗西汀与阿米替林治疗酒依赖伴有的抑郁焦虑的疗效和安全性。方法:将50例酒依赖患者随机分为两组,分别给予帕罗西汀与阿米替林治疗,疗程6周,用汉密顿焦虑量表(HAMA)及汉密顿抑郁量表(HAMD)评定临床疗效,用副反应量表(TESS)评定不良反应。结果:两组均有显著疗效,两组间无显著性差异,但帕罗西汀组的不良反应较阿米替林少且轻。结论:帕罗西汀治疗酒依赖伴有的焦虑抑郁症状安全有效,不良反应小。
Objective：To compare the efficaly and side effects of Paroxetine and Amitriptyline in the treatment of depression and anxiety by alcohol deperdence. Methods ：50 patients with alcohol deperdence were randomly assigned to Paroxetine group and Am- itriptyline group for 6 weeks, the efficacy and side effects were rated with HAMD, HAMA and TESS. Results： Both drugs had marked efficacy in the treatment of depression and anxiety by alcohol deperdence, there was no significantly difference between two groups, Paroxetine had significantly fever side effects than Amitriptyline. Conclusions： Paroxetine is safe and effective with slight side effects for depression and anxiety by alcohol deperdence.
出处
《中国民康医学》
2010年第23期3048-3049,共2页
Medical Journal of Chinese People’s Health
关键词
帕罗西汀
阿米替林
酒依赖
焦虑
抑郁
Paroxetine
Amitriptyline
Alcohol deperdence
Depression
Anxiety by
