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老年慢性心力衰竭脑钠肽的动态变化及应用脑钠肽治疗的临床观察 被引量:4

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摘要 为研究慢性心衰患者脑钠肽的变化及应用冻干重组人脑钠肽治疗的心衰患者临床效果。检测30例慢性心衰患者B型脑钠肽前体,同时观察应用冻干重组人脑钠肽粉针(新活素)的治疗效果及相关指标心率、血压、心功能分级、谢血分数(EF)、肌酐及脑钠肽的变化。结果显示心功能不全组脑钠肽治疗后心功能大部分得到改善,其中显效11例、有效9例、无效3例、加重2例,死亡5例,其中因心衰死亡2例。心衰组B型脑钠肽前体明显升高。心衰组治疗后B型脑钠肽下降,射血分数上升,心率下降,血压及肌酐无明显差异,但血压有下降趋势。结论:脑钠肽在慢性心衰患者中水平升高,B型重组人脑钠肽治疗慢性心衰有效,且长期安全应用也比较安全。
出处 《沈阳部队医药》 2010年第6期368-369,共2页
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参考文献5

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