摘要
为探讨麻疹疫苗再免疫的效果，对珠海市香洲区按免疫程序8月龄、3岁、7岁进行麻疹疫苗（MV）接种的3岁、7岁儿童共196人，进行了再免疫效果评价。结果表明：再免疫前、后麻疹抗体阳性率分别为96．43％和100％，几何平均滴度（GMT）分别为1：805和1：4557。再免疫成功率与再免疫前抗体滴度呈负相关，再免疫前抗体滴度＜1：200、1：200、1：800、1：3200的，再免疫成功率分别为100％、97.06％、94．07％、71.88％；3岁与7岁间再免疫成功率的差异无显著的统计学意义．初免（8月龄）后2年、再免疫（3岁）后4年，麻疹抗体滴度均处在低抗体水平，显示麻疹再免疫具有重要的意义，再免疫年龄3岁比较合适．
The article presented here is to evaluate the reimmunization effect of measles vaccine on a total of 196 children of 3 and 7 years old who had been inoculated according to the schedule of 8 months, 3 years and 7 years. The results showed that the measles antibody positive rate and GMT after reimmunization were 100% and 1: 4557 as compared with that of 96.43% and 1: 805 before reimmunization respectively (p<0.01). There was a negative relationship between reimmunization successful rate and the measles antibody titer prior to reimmunization . The lower the measles antibody before reimmunization (<1: 200), the higher the reimmunization successful rate (100%) was tested by ELLSA,and similarly the higher the measles antibody before reimmunization (1: 3200) the lower the successful rate (71.88%). No significant statistical difference had been found about the reimmunization successful rate between children of 3 and 7 years old.2 years after first measles immunization 8 months and 4 years after first reimmunization 3 years old, the titers of measles antibody were mostly at a low level, this suggests that the age for reimmunization is better at 3 years old.
出处
《中国计划免疫》
1999年第2期99-101,共3页
Chinese Journal of Vaccines and Immunization
关键词
麻疹疫苗
再免疫
效果
Measles vaccine
Reimmunization
Evaluation
