摘要
目的:应用放射性生物微球测量器官组织血流量的方法,观察大承气汤对急性细菌性腹膜炎家兔主要脏器血流量的影响。方法:实验中应用一种改良的99mTc标记蛙红细胞的方法,用LKB1620γ记数器测定各主要器官的放射性,计算出其血流量。结果:中药治疗组家兔的腹腔大部分脏器血流较腹膜炎组明显增加(P<0.01)尤其是肾血流量成倍增加,为模型组的47倍,且间接增加肝脏血流。结论:大承气汤对急性细菌性腹膜炎机体功能的改善、肝脏的代谢功能和肾脏排毒功能的提高起相当重要的作用。
Objective:To observe the influence of Chinese herbal medicine(Da Cheng Qi Tang)on the blood flow of main organs of rabits suffering from acute bacterial peritonitis by using redionuclide labeled particles. Methods:Using Tc 99m RBC of frogs to test radioactivity and blood flow of several organs with a LKB 1620γ counter. Results:In the herbal treated group the blood flow of most of the rabit organs were increased especially the renal blood flow which was increased as much as 4.7 times of the normal.The hepatic blood flow was also increased indirectly.Conclusion:DaChengQi Tang could improve the body resistance in rabbits suffering from acute bacterial peritonitis, through the improvement of detoxication of the liver and excretion of toxins by the kidney. These effects might be the therapeutic,mechanism basis of the effectiveness of Da Cheng Qi Tang.
出处
《中国中西医结合外科杂志》
CAS
1999年第2期114-116,共3页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
急性
细菌性
腹膜炎
器官血流量
大承气汤
acute bacterial peritonitis,radionuclide labeled particles,visceral blood flow,Da Cheng Qi Tang