摘要
目的筛选影响骨密度的相关因素，降低人群骨质疏松的患病率。方法60岁以下健康体检成人46219例，进行人体学测量及血脂、血糖、电解质离子，尿酸、同型半胱氨酸等指标的检测，并应用Mestriscan^TM骨密度仪检测手部指骨的平均骨密度（BMD），描述性的分析了不同性别随龄性的BMD变化情况及骨质疏松的患病率，并应用简单相关及多元逐步回归分析了影响BMD的相关因素。结果男性与女性相比，除年龄外，其他所有研究因素差异均有统计学意义。女性的平均BMD低于男性（0．50±0．15vs0．54±0．15，t=22．38，P〈0．05），女性的骨质疏松发生率高于男性（29．51％vs26．48％，X^2=47．90，P〈0．05）；40岁前男性与女性的BMD随年龄增加而增大，之后，随着年龄增大，男性与女性的BMD均呈下降趋势，且女性的BMD在50岁后有明显的下降。结论在本研究中男性骨密度高于女性，吸烟、腰臀比、收缩压、血钙、总胆固醇、碱性磷酸酶是男性与女性骨密度的共同负相关因素。
Objective To investigate bone mineral density-related factors to decrease the prevalence of osteoporosis. Methods This cross-sectional survey enrolled 46 219 adults less than 60 years old. Anthropometry, blood pressure, serum lipid, glucose, electrolytes, uric acid and homocysteine were detected. Bone mineral density （BMD） of distal forearm was measured by using peripheral dual energy-ray detector （ MestriscanTM ）. Our data were analyzed by Pearson＇ s correlation analysis and stepwise multiple regression analysis. Results All BMD-related factors except age showed significant difference between male and female. BMD of female subjects was lower than that of male participants （0. 50± 0. 15 vs 0. 54 ±0. 15, t =22. 38 ,P 〈 0. 05 ）. The prevalence of osteoporosis in female was higher （ 29. 51% vs 26.48%, x^2 = 47. 90 ,P 〈 0. 05 ）. BMD increased with age before 40-year old, and then decreased more rapidly in female after 50-year old. Conclusion BMD of male is higher. Cigarette smoking, waist-hip ratio, systolic blood pressure, serum sodium, total cholesterol, and ALP were negatively correlated with BMD.
出处
《中华健康管理学杂志》
CAS
2010年第6期340-343,共4页
Chinese Journal of Health Management
关键词
骨密度
骨质疏松
体格检查
Bone density
Osteoporosis
Physical examination
