摘要
目的：介绍近几年丹参酮ⅡA对心血管保护作用的研究进展,并探讨其可能的机制.方法：查阅和归纳总结近几年相关文献.结果：丹参酮ⅡA具有抗血小板聚焦作用,对心、肝,脑细胞具有保护作用;具有抗急性缺氧,保护心肌,防治冠心病作用;具有抑制血管平滑肌细胞增殖,抗动脉粥样硬化作用,对血管内皮细胞具有保护作用;具有抗心律失常作用;减轻心肌肥厚,保护心肌等多种心血管保护作用.结论：丹参酮ⅡA是中药丹参中一种非常有效的脂溶性成分,其药理作用显著,具有广阔的临床应用前景.
Objective： Introduction in recent years, tanshinone Ⅱ A protective effect on cardiovascular research and to explore its possible mechanism. Methods： Search and summarize the literature in recent years. Result： Tanshinone Ⅱ A focus with anti-platelet effect on the heart, liver, brain cells play a protective role; With anti-acute hypoxia, myocardial protection, coronary heart disease prevention and control role; can inhibit vascular smooth muscle cell proliferation, anti-atherosclerosis effect. On vascular endothelial cells play a protective role; with antiarrhythmic effect; reduce cardiac hypertrophy, myocardial protection and other cardiovascular protection.Conclusion： Tanshinone ⅡA is the TCM Danshen in a very effective fat-soluble components, the significant pharmacological effects, is worth being clinically applied.
出处
《中医临床研究》
2010年第22期5-7,共3页
Clinical Journal Of Chinese Medicine
关键词
丹参酮ⅡA
心血管保护
丹参
Tanshinone Ⅱ A
Cardioprotective
Salvia miltiorrhiza
