摘要
目的:了解缺血性卒中住院患者一、二级预防抗栓药物的应用现状,为该类患者二级预防合理使用抗栓药物提供参考。方法:研究对象为急性脑梗死住院患者,对其出院带药(方案)进行用药指导,同时调查其入院之前卒中一、二级预防抗栓药物的应用状况。结果:入选患者共178例,其中第1次发作106例,使用抗栓药物者36例(一级预防抗栓药物使用率34%),第2次及以上发作72例,使用抗血栓药物者56例(二级预防78%);在92例使用抗栓药物进行卒中一、二级预防的患者中,以规范的剂量和频次服用阿司匹林和氯吡格雷者56例(61%);长期服药者46例(坚持服药率50%)。结论:缺血性卒中患者一、二级预防抗栓药物的应用现状不容乐观,存在其应用比例较少、剂量不足、服药间断现象。临床医生、药师应对缺血性卒中患者一、二级预防抗栓药物的合理使用应给予正确、全面指导,以提高用药的依从性。
OBJECTIVE To investigate the status of the application of antithrombotic in primary and secondary prevention of ischemic stroke and to provide reference for improving the secondary prevention. METHODS The study was a cross sectional investigation. All inpatients in diagnosis of acute cerebral infarction were guided for discharge medication and we inw.stigated the application of antithrombotic before admission. RESULTS 178 patients were involved, the cases of first stroke attack were 106, among them 36 patients applied antithrombotic, the cases of second and above stroke altack were 72, among them 56, patients applied antithrombotic. 56 cases were administrated aspirin and clopidogrel in slandard dose and frequeney of 92 patients. The cases of continous use of antithrombotic were 46 （compliance rate is 50%）. CONCLUSION The status of the application of antithrombotic in primary and secondary prevention on acute ischemic stroke was not optimistic, there was a small proportion and low dose and discontinuance of application of antithrombotic. Doctors and pharmacists should pay attention to the compliance of antithrombotic in primary and secondary prevention of ischemic stroke.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2010年第22期1930-1933,共4页
Chinese Journal of Hospital Pharmacy
关键词
缺血性卒中
一
、二级预防
抗栓药物
ischemic stroke
primary and secondary prevention
antithrombotic
