摘要
试验选用14日龄健康雏鸡154只,随机分为5个感染药物组、1个阳性组和1个阴性组,每组22只。采用POAA、RLS、ROP和ACI综合评定QHD-08株柔嫩艾美耳球虫的耐药谱。结果显示,QHD-08株柔嫩艾美耳球虫对尼卡巴嗪呈现中度耐药,对克球粉、氨丙啉、马杜霉素和瑞冠球均呈现完全耐药;在2004-2008年期间,QHD株柔嫩艾美耳球虫对氨丙啉的耐药变迁结果为无耐药性→轻度耐药→完全耐药;对尼卡巴嗪的耐药性由2006年轻度耐药转变为2008年中度耐药,而克球粉、马杜霉素、氨丙啉和瑞冠球等4种抗球虫药的耐药性均从2006年的轻度(或中度)耐药转变为2008年的完全耐药。结果表明,QHD株柔嫩艾美耳球虫对常用抗球虫药物的耐药谱宽,且耐药率呈逐年递增的趋势。
The resistance spectrum changes of Eimeria tenella（E.tenella） Qinhuangdao（QHD-08） strain in the 2004-2008 period were studied.One hundred and fifty four,14,days old,healthy chickens were divided randomly into 7 groups of 22 each,5 medicated groups,one positive group and one negative group.Based on the POAA,RLS,ROP and ACI,the drug resistances of E.tenella QHD strain were detected.The results revealed that the E.tenella QHD-08 strain was middle resistant to nicarbazin and complete resistant to amprolium,maduramicin,keqiufen and ruiguanqiu.In the 2004-2008 period,resistance spectrum changes of E.tenella QHD strain to amprolium were non-resistant→light resistant→complete resistant.The resistances of E.tenella QHD strain changed from light resistant of 2006 to middle resistant of 2008 to nicarbazin,and light or middle resistant of 2006 to complete resistant of 2008 to maduramicin,keqiufen,amprolium and ruiguanqiu.The results revealed that resistance spectrum of E.tenella strain to common anticoccidial drugs was broad,and resistance rate was increasing in recent years.
出处
《中国兽医学报》
CAS
CSCD
北大核心
2010年第11期1472-1475,共4页
Chinese Journal of Veterinary Science
基金
河北省自然科学基金资助项目(C2006000554)
