摘要
细胞因子信号传导抑制蛋白(suppressor of cytokine signaling,SOCS)家族是一类由细胞产生并反馈性阻断细胞因子信号转导过程的负性调节因子。SOCS1是其重要成员之一,参与多种细胞因子的信号转导及免疫细胞的形成与分化,对机体固有免疫和适应性免疫反应起到重要的调控作用。本文就SOCS1对免疫调节的研究进展进行综述。
Suppressor of cytokine signaling（SOCS） proteins have been identified as inducible feedback inhibitors of cytokine signal transduction and produced by cells.SOCS1 belongs to SOCS protein families,participates in the cytokine signal transduction,the development and differentiation of immune cells,moreover it modulates both innate and adaptive immunity as one of key physiological regulators.
出处
《免疫学杂志》
CAS
CSCD
北大核心
2010年第11期1008-1011,共4页
Immunological Journal
