摘要
目的探讨新定义短暂性脑缺血发作(TIA)与脑梗死的临床及影像学特点的区别。方法对41例传统定义的TIA患者(其中按TIA新定义24例诊断为TIA,17例为脑梗死)进行临床资料搜集和头颅CT、MRI检查。结果新定义TIA组的症状持续时间[(18±6.5)min]、肢体无力和失语的比率(45.8%,0%)均明显小于脑梗死组[(55±10.6)min,76.5%,29.4%](P<0.05～0.001),两组颈动脉硬化、高血压病、心脏病、糖尿病、房颤、高脂血症的差异无统计学意义。新定义TIA组头颅CT和常规MRI发现异常分别为10例(41.7%)和24例(100%),脑梗死组分别为6例(35.3%)和14例(82.4%),两组的差异无统计学意义。新定义TIA组弥散加权成像(DWI)检查均无脑部高信号影,脑梗死组DWI均有脑部局灶高信号影,位于皮质5例,皮质下12例。结论新定义TIA患者的症状持续时间短,肢体无力和失语的比率低,DWI无脑部高信号影。DWI可区别TIA与脑梗死。
Objective To investigate the distinction of clinical and imaging features between newly defined transient ischemic attack （TIA） and cerebral infarction（CI） . Methods Clinical data of 41 traditionally defined TIA patients （including 24 newly defined TIA patients and 17 CI patients） were collected. And all the patients were detected by CT and MRI. Results The prolonged duration [（18 ± 6. 5 ） min],dyskinesia rate （45. 8% ） and aphasia rate （0% ） of newly defined TIA group were significantly less than those of CI group [（55 ± 10. 6） min, 76. 5% ,29. 4% ],respectively （P 0. 05 - 0. 001） . There was no significant difference between the two groups in carotid artery sclerosis,hypertension,cardiac disease,diabetes,atrial fibrillation and hyperlipemia. In newly defined TIA group,abnormality was found in 10 cases （41. 7% ） by CT and 24 cases （100% ） by MRI; while in CI group,it was found in 6 cases （35. 3% ） by CT and 14 cases （82. 4% ） by MRI. And there was no significant difference between the two groups. The high signal was not found in newly defined TIA group by DWI,but was found in CI group （with 5 cases at cortex and 12 cases at subcortex） by DWI. Conclusions Of newly defined TIA patients,the prolonged duration is short,the dyskinesia rate and aphasia rate are low,and there is no high signal in DWI. DWI can distinguish between CI and TIA.
出处
《临床神经病学杂志》
CAS
北大核心
2010年第5期375-377,共3页
Journal of Clinical Neurology
关键词
短暂性脑缺血发作
脑梗死
弥散加权成像
transient ischemic attack
cerebral infarction
diffusion-weighted imaging
