期刊文献+

高渗盐水雾化吸入治疗小儿毛细支气管炎效果观察 被引量:13

Effect observation of bronchiolitis in children treated with aerosol inhalation of hypertonic saline
下载PDF
导出
摘要 目的观察高渗盐水雾化吸入辅助治疗毛细支气管炎的疗效。方法 90例患者随机分为观察组43例和对照组47例。2组均采用相同方法进行综合治疗,观察组给予雾化吸入高渗盐水,对照组给予雾化吸入盐酸氨溴索。观察2组疗效以及症状、体征持续时间和住院时间。结果观察组总有效率为97.7%高于对照组的91.5%,差异有统计学意义(P<0.05);观察组哮鸣音、咳嗽消失时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。结论雾化吸入高渗盐水辅助治疗小儿毛细支气管炎疗效明显优于雾化吸入盐酸氨溴索,值得临床推广应用。 Objective To observe the efficacy of bronchiolitis in children treated with aerosol inhalation of hypertonic saline for adjutant treatment. Methods 90 cases were randomly divided into observation group of 43 and control group of 47. Both groups were given comprehensive treatment by the same way. The observation group was given aerosol inhalation of hypertonic saline,while the control group was given aerosol inhalation of ambroxol hydrochloride. Observed 2 groups' efficacy,lasting time of symptoms and signs,and length of stay. Results The total effective ratet of the observation group was 97. 7% higher than 91. 5% of the control group,and the difference was statistically significant( P〈0. 05). The extinction time of wheezing and cough was shorter than that of the control group,so was the length of stay,and the differences were statistically significant ( P〈0. 05). Conclusion Treating bronchiolitis in children with aerosol inhalation of hypertonic saline for adjutant treatment has remarkablely better efficacy than ambroxol hydrochloride,which is worth clinical popularizing and application.
作者 杨开颜 陈麒
出处 《临床合理用药杂志》 2010年第21期22-23,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 毛细支气管炎 小儿 高渗盐水 雾化吸入 Bronchiolitis children Hypertonic saline Aerosol inhalation
  • 相关文献

参考文献6

二级参考文献21

  • 1中华人民共和国卫生部.小儿肺炎防治方案[J].中华儿科杂志,1987,25:47-47. 被引量:524
  • 2[1]Gillissen A, Nowak D. Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. Respir Med, 1998, 92:609-623. 被引量:1
  • 3[2]Teramoto S, Suzuki M, Ohga E, et al. Effects of ambroxol on spontaneous or stimulated generation of reactive oxygen species by bronchoalveolar lavage cells harvested from patients with or with-out chronic obstructive pulmonary diseases. Pharmacology,1999, 59:135-141. 被引量:1
  • 4[3]Gillissen A, Bartling A, Schoen S, et al. Antioxidant function of ambroxol in mononuclear and polymorphonuclear cells in vitro. Lung, 1997, 175:235-242. 被引量:1
  • 5[4]Park NH, Han ES, Lee CS, et al. The inhibitory effect of ambroxol on respiratory burst, de granulation and cytosolic Ca2+ change in degraded immunoglobulin G-activated neutrophils. Pharmacol Toxicol, 1999, 84: 81-87. 被引量:1
  • 6[5]Pfeifer S, Zissel G, Kienast K, et al. Reduction of cytokine release of blood and bronchoalveolar mononuclear cells by ambroxol. EurJ Med Res, 1997, 2:129-132. 被引量:1
  • 7[6]Stettner S, Ledwozyw A. The effect of Ambroxol on bleomycininduced changes in phospholipid composition of rat lung surfactant. Acta Physiol Hung, 1995, 83:181-187. 被引量:1
  • 8[7]Mira E, Benazzo M, De Paoli F, et al. Surfactants of the air-ways. Critical review and personal research. Acta Otorhinolaryngol Ital, 1997, 17(1 Suppl 56):3-16. 被引量:1
  • 9[8]Nemcekova E, Nosalova G, Franova S. Ambroxol and protective reflexes of the respiratory tract. Bratisl Lek Listy, 1998, 99:111-115. 被引量:1
  • 10[9]Tyrakowski T, Greczko Ⅰ, Sedlaczek A, et al. Electrophysiological investigation of the effects of ambroxol on the transepithelial Na + ion transport pathway in airways. Pol J Pharmacol,1998, 50:31-38. 被引量:1

共引文献2251

同被引文献81

引证文献13

二级引证文献146

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部