摘要
脑缺血患者入院后血糖通常会大幅度升高,从而导致预后较差。为此,采用胰岛素快速而稳定地降低血糖是很重要的治疗措施。然而,迄今为止,关于胰岛素治疗脑卒中的临床研究还未能得出一个统一明确的治疗方案,而胰岛素的使用也因为其导致低血糖等不良反应而备受限制。在此,本文总结了脑缺血后血糖的变化、胰岛素的保护机制以及目前常用的控制血糖方法,为将来进行临床研究提供参考。
Patients with acute ischemic stroke frequently test positive for hyperglycemia after admitted into hospital,which is associated with a poor clinical outcome.Thus,to control plasma glucose within an optimal level is essential for treat-ment.Yet,to date,the clinical researches about this area can not generate a clear and formal protocol.Therefore,we high-light the alterations in blood glucose after ischemia-reperfusion injury,the molecular mechanism of Insulin ′s protective ac-tions and the most usually used regimens for glycemic control as reference for any ongoing Insulin-stroke researches.
出处
《中国医药导报》
CAS
2010年第32期9-11,共3页
China Medical Herald
