摘要
目的探讨血脂异常对冠心病相关危险因素的影响,以及它们之间的危险度。方法从笔者所在医院门诊就诊患者及干部年度健康体检者中随机抽取430例各型高脂血症患者,并在正常对照组中随机抽取160例,分别检测它们的血脂水平,以及分析它们发生冠心病的危险度,并以吸烟、肥胖(体重指数)为辅助因素计算其调整危险度。结果Ⅰ型、Ⅱ型、Ⅲ型和Ⅳ型高脂血症的冠心病患病率分别为52.10%、55.20%、56.60%和63.44%;对照组的冠心病患病率分别为28.33%和20.00%,与对照组比较,均有显著性差异(P.<0.01)。Ⅰ型、Ⅱ型、Ⅲ型、Ⅳ型高脂血症患者与冠心病的调整相对危险度分别是对照组的4、5、6、7倍。结论血清甘油三酯、胆固醇、高密度脂蛋白异常时冠心病发生的危险度均会升高,高脂血症是冠心病发病最强的预告信号,是重要的可调性间接危险因素之一,控制血脂、戒烟、合理饮食、降低超重和肥胖是预防冠心病的有力措施。
Objective To investigate the effect of Dyslipidemia on the level of related risk factors of coronary heart disease and risk among them. Methods 430 cases of various types of Hyperlipidemic Patients from author＇hospital were randomly selected and the healthy volunteers in the annual Physical examination and i60 from the control group cases. Their serum lipids levels respectively were tested and their risk of the occurrence of coronary heart disease were analyzed with smoking, obesity（ body mass index）as contributing factors to calculate the adjusted risk. Results Ⅰ , Ⅱ , Ⅲ and Ⅳ Hyperlipidemia prevalence of coronary heart disease were 52.10%, 55.20%, 56.60% and 63.44% respectively; The control goup were 28.33 % and 20.00%, there were significant differences compared with the control group （ P 〈 0.01 ）. The adjusted relative risk were 4,5,6,7. Conclusion Abnormal level of Serum triglyceride, cholesterol and high density lipoprotein will lead to in- creased risk of coronary heart disease, Hyperlipidemia is the strongest warning signal for the occurrence of coronary heart dis- ease and an important indirect risk factor which is adjustable. Control of blood lipids, smoking cessation, proper diet, reduce overweigt and obesity are effective measures to prevent coronary heart disease.
出处
《中国医学创新》
CAS
2010年第32期5-7,共3页
Medical Innovation of China
关键词
各型高脂血症
冠心病
危险度分析
Hyperlipidemia
Coronary heart disease
Risk analysis
