摘要
目的考察盐酸氨溴索注射液与葡萄糖酸依诺沙星注射液配伍的稳定性。方法在室温[(20±1)℃],避光条件下,盐酸氨溴索与葡萄糖酸依诺沙星配伍后0～6 h内测定pH,观察外观及性状变化,采用高效液相色谱法-二极管阵列检测器测定盐酸氨溴索与葡萄糖酸依诺沙星的含量变化。结果 6 h内混合液外观、pH及含量均无明显变化。结论在室温[(20±1)℃]避光条件下,盐酸氨溴索注射液与葡萄糖酸依诺沙星注射液6 h内可以配伍使用。
Aim To study the compatible stability of ambroxol hydrochloride injection in enoxacin gluconate injection.Methods At room temperature [（20 ± 1） ℃],the changes in contents of ambroxol hydrochloride and enoxacin were determined by HPLC-DAD,and the changes in appearance,pH were observed away from light at（20 ± 1） ℃ within 6 hours.Results No significant changes were found in the contents,appearance and pH value for the mixed solution within 6 hours.Conclusion Ambroxol hydrochloride injection can be mixed with enoxacin gluconate injection away from light at（20 ± 1） ℃ within 6 hours.
出处
《安徽医药》
CAS
2010年第12期1391-1393,共3页
Anhui Medical and Pharmaceutical Journal
