摘要
建立了用超快速液相色谱（UFLC）仪测定甲基苯丙胺含量的方法。采用XR—ODS柱，流动相为0．05％磷酸-甲醇（85：15），流速为0．4mL／min，检测波长为215nm。该法在1—5000μg/mL浓度范围内线性关系良好，r2=0．9998，目内与日间保留时间和峰面积的相对标准偏差均小于6％，样品的加标回收率为92．4％～116．7％，检出限为0．68μg/mL。该方法适用于甲基苯丙胺的定性定量分析。
method for detecting methamphetamine by UFLC using XR - ODS column was established. The mobile phase was phosphate（0.05% ） - methanol （85： 15） , at a flow rate of 0.4 mL/min, with 215 nm as the detection wavelength. The method had good linearity at the range from 1 to 5 000 μg/mL, r2 = 0. 999 8. Both intra- day and inter- day precisions expressed by relative standard deviations of retention time and peak area were less than 6%. The recovery was 92.4% - 116.7%. The detection limit was 0.68 μg/mL. The method is suitable for qualitative and quantitative analysis.
出处
《化学分析计量》
CAS
2010年第6期67-68,共2页
Chemical Analysis And Meterage
