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米索前列醇用于足月妊娠引产剂量的探讨

Semen Analysis Report on 376 Cases Normal Buyi Nationality in Guizhou
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摘要 为了探讨米索前列醇含服用于足月妊娠引产的临床合理剂量,选择有引产指征,无引产及米索前列醇使用禁忌症的单胎、头位的足月妊娠妇女72例,随机分为A,B,C三组,分别用米索前列醇25μg、50μg、75μg/次含服,间隔4~6h重复给药,24h内最大剂量为200μg。结果:A组、B组与C组引产成功率分别为750%、9006%和908%。首次用药至规律宫缩开始时间分别为1283±598h、682±221h和635±342h,首次用药至胎儿娩出时间分别为1633±765h、860±442h和882±487h。A组与B,C组比较,差异有显著性(P<005),B组与C组比较,差异无显著性(P>005)。但宫缩过强伴胎儿监护异常的发生率A组和B组低于C组。提示:50μg剂量米索前列醇用于足月妊娠引产较为合理。 We present here the results of semen analysis from 376 cases normal Buyi nationality in Guizhou province. Evaluated spermatozoa parameters were as following:Semen volume was 1.0 4.0 ml; Liquefaction of 30 min after collection. The pH was at 6.8-8.0; Sperm vitality was 57%-83%;55%-79% of the sperm was normal morsphologically;Spermatozoa concantration was 23.6-163.7×10 6/ml; The spermatozoa motility was expressed in four scales of a to b (a and b degree were 4%-11% and 48%-73% respectively) No-sperm cells was 1-4/HP. We fond that some of the evaluated parameters differed somewhat from reported one. This could be caused by the experimental procedures, nationality and environment factorts and other unknow causes.
出处 《贵阳医学院学报》 CAS 1999年第1期47-49,共3页 Journal of Guiyang Medical College
关键词 米索前列醇 足月妊娠 药物引产 剂量 spermatozoa semen Buyi nationality
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