摘要
目的探讨早期高压氧联用自由基清除剂(依达拉奉)治疗急性脑梗死的疗效。方法选择2009年8月～2010年3月收治急性脑梗死病人48例,随机分为治疗组22例,对照组26例,治疗组在对照组基础上加用自由基清除剂依达拉奉,30mg,每日两次;并早期采取高压氧治疗,每日一次,其余治疗措施两组相同。疗程为14天,观察两组病人治疗前后的欧洲卒中量表(european stroke score ESS)和美国国立卫生研究院卒中量表(NIHStroke Scale NIHSS)评分变化。结果治疗后14d,治疗组患者的ESS评分均显著高于对照组(P<0.05),NIHSS评分显著低于对照组(P<0.05)。结论早期高压氧联用自由基清除剂(依达拉奉)治疗急性脑梗死患者有较好临床疗效。
Objective Discuss the curative effect of early hyperbaric oxygen combined with free radical scavenger （edaravone）. Methods There are 48 cases of diagnosed patients with acute cerebral infarction, including 22 cases were randomly divided into treatment group and control group is 26 cases, The treatment group on the basis of the control group was added free radical scavenger edaravone needle 30rag, using twice a day, hyperbaric oxygen（HBO） therapy was added, using once a day. 14d is a course of treatment. The remaining two sets of the same treatment measures. Observed the change before and after of treatment refering to the European Stroke Scale （ESS） and the U.S. National Institutes of Health Stroke Scale （NIHSS）.Results After treatment 14d, the treatment group of patients with ESS scores were significantly higher （P〈0.05）, and the NIHSS scores were significantly lower（P〈0.05）.Conclusion It have a better clinical effection in patients with early hyperbaric oxygen combined with free radical scavenger（edaravone）of acute cerebral infarction.
出处
《当代医学》
2010年第31期8-9,共2页
Contemporary Medicine
关键词
早期
高压氧
自由基清除剂
急性脑梗死
Early
Hyperbaric oxygen
Free radical scavenger
Acute cerebral infarction
