摘要
目的探讨自身免疫性荨麻疹的临床特点、病理改变、免疫学特征和治疗方法。方法回顾性分析60例自身免疫性荨麻疹患者的自体皮肤血清试验(autoallergic skin serum test,ASST)、器官特异性自身抗体的检测结果、临床特点以及治疗等。结果 592例慢性荨麻疹患者中ASST阳性者82例(阳性率为13.85%),其中有60例检测出器官特异性自身抗体。皮肤损害的临床表现与普通的慢性荨麻疹无明显差异,但是持续时间比较长;9例患者合并结缔组织病,28例合并桥本甲状腺炎。结论自身免疫性荨麻疹具有自身免疫的背景,与系统性红斑狼疮等结缔组织病合并存在的现象值得注意。
Objective To investigate the clinical characteristics, pathological changes, immunological characteristics, and therapy of autoimmune urticaria. Methods The autoallergic skin serum test （ASST）, organ- specific autoantibody, clinical characteristics, and therapy of 60 patients with autoimmune urticaria were retrospectively analyzed. Results Among 592 patients with chronic urticaria, 82 showed positive ASST （13.85%） , and 60 had organ -specific autoantibody. There were no significant differences with common chronic urticaria in the clinical manifestation of skin lesion, but the duration was longer; Five patients were complicated with connective tissue disease, and 32 with Hashimoto＇s thyroiditis. Conclusion Autoimmune urticaria has an autoimmune background, and it should be noticed that autoimmune urticaria coexist with systemic lupus e^ythematosus and other connective tissue diseases.
出处
《河北医科大学学报》
CAS
2010年第10期1195-1197,共3页
Journal of Hebei Medical University
关键词
荨麻疹
血清学试验
免疫
urticaria
serologic tests
immunity
