摘要
目的 探讨核磁共振（MR）和数字减影血管显影（DSA）联合应用对肝硬化结节（再生结节、退变结节）转变成小肝癌的早期诊断价值.方法 40例临床诊断为肝硬化、超声检查发现肝硬化结节灶的患者作为MR动态随访的研究对象.全部病例均每3个月一次MR三期动态增强扫描,观察肝硬化结节信号变化并作对比分析,如MRI提示肝硬化结节癌变则行肝动脉DSA检查.结果 40例患者随访时间为1.5～3年,全部病例MR检查均显示肝内再生结节.随访过程中,发现退变结节28例,小肝癌18例.18例小肝癌患者中16例行DSA检查,均有典型的肝动脉供血及肿瘤血管生成,同时给予中西医结合介入治疗.结论 MRI-DSA联合应用对评价肝硬化结节病灶的演变过程具有肯定的价值,能及时发现小肝癌,为小肝癌的介入治疗提供依据.
Objective To evaluate the early diagnosis value of MRI combined with DSA in cirrhotic nodules （regenerative nodules, dysplastic nodules） becoming small hepatocellular carcinoma. Methods 40 patients diagnosed as cirrhosis and whose liver nodules detected by ultrasound were followed up as MR dynamic study. All patients were followed up by three dynamic contrast-enhanced MR scanning once every 3 months,and the changes of cirrhotic nodules were observed and analyzed in the signal. If MRI suggested cancerous nodules cirrhosis, hepatic artery DSA would be carried out. Results 40 patients were followed up for 1.5 to 3 years,all patients MR nodules were found in liver regeneration. Follow-up process, the dysplastic nodules were founded in 28 cases and the small hepatocellular carcinoma were founded in 18 patients. 16 cases of 18 patients with small hepatocellular carcinoma carried out routine DSA all had typical of hepatic arterial blood supply and angiogenesis, and were given to Integrated Traditional and Western intervention simultaneously. Conclusion Combined use of MRI-DSA in the evaluation of cirrhotic nodules had a definite value, and could find smaller hepatocellular carcinoma,provide the basis for smaller hepatocellular carcinoma therapy.
出处
《中国基层医药》
CAS
2010年第20期2745-2747,共3页
Chinese Journal of Primary Medicine and Pharmacy
基金
广东省深圳市科技局立项项目（200803122）
关键词
肝硬化结节
小肝癌
核磁共振成像
数字减影血管造影
Cirrhotic nodules
Smaller hepatocellular carcinoma
Magnetic resonance imaging
Digital subtraction angiography
