1Tontonoz P,Hu E,Spiegelman B M.Stimulation of adipogenesis in fibroblasts by PPAR gamma 2,a lipid-activated transcription factor[J].Cell,1994,79:1147-1156. 被引量:1
2Evans R M,Barish G D,Wang Y X.PPARs and the complex journey to obesity[J].Nat Med,2004,10:355-361. 被引量:1
3Nagy L,Tontonoz P,Alvarez J G,et al.Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR gamma[J].Cell,1998,93:229-240. 被引量:1
4Zhang L,Chawla A.Role of PPAR gamma in macrophage biology and atherosclerosis[J].Trends Endocrinol Metab,2004,15:500-505. 被引量:1
5Moore K J,Rosen E D,Fitzgerald M L,et al.The role of PPAR-gamma in macrophage differentiation and cholesterol uptake[J].Nat Med,2001,7:41-47. 被引量:1
6Jiang C,Ting A T,Seed B.PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines[J].Nature,1998,391:82-86. 被引量:1
7William W B,Robert F L.Asthma[J].N Engl J Med,2001,344:350-362. 被引量:1
8Honda K,Marquillies P,Capron M,et al.Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model[J].J Allergy Clin Immunol,2004,113:882-888. 被引量:1
9Narala V R,Ranga R,Smith M R,et al.Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma[J].Respir Res,2007,8:90. 被引量:1
10Lee K S,Park S J,Kim S R,et al.Modulation of airway remodeling and airway inflammation by peroxisome proliferator-activated receptor gamma in a murine model of toluene diisocyanate-induced asthma[J].J Immunol,2006,15(177):5248-5257. 被引量:1
2Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell, 1997,89: 587-596. 被引量:1
3Szabo SJ, Kim ST, Costa GL, et al. A novel transcription factor, T-bet,directs Th1 lineage commitment. Cell, 2000, 100: 655-669. 被引量:1
4Daynes RA, Jones DC. Emerging roles of PPARs in inflammation and immunity. Nat Rev Immunol, 2002, 2: 748-759. 被引量:1
5Clark RB, Bishop-Bailey D, Estrada-Hernandez T, et al. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol, 2000, 164: 1364-1371. 被引量:1
6Chung SW, Kang BY, Kim TS, et al. Inhibition of interleukin-4 production in CD4^+ T cells by peroxisome proliferator-activated receptor-gamma(PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. Mol Phammacol, 2003, 64: 1169-1179. 被引量:1
7Hamida H, Hendrik JdH, Thomas S, et al. Activation of peroxisome proliferator-activated receptor in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma. AJP,2004, 164: 263-271. 被引量:1
9Honda K, Marquillies P, Capron M, et al. Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. J Allergy Clin Immunol, 2004,113: 882-888. 被引量:1
10Zhang DH, Yang L, Cohn L, et al. Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant GATA-3. Immunity, 1999, 11: 473-482. 被引量:1
6Issemann I,Green S.Activation of anumber of the steroid recep-tor superfamily by peroxisome proliferators[J].Nature,1990,347(6294):645-650. 被引量:1
7Voytovich MH,Simonsen C,Jenssen T,et al.Short-term treatmentwith rosiglitazone improves glucose tolerance,insulin sensitivity andendothelial function in renal transplant recipients[J].Nephrol DialTransplant,2005,20(2):413-418. 被引量:1
8Narala VR,RangaR,SmithM R,et al.Pioglitazone is as effective asdexamethasone in a cockroach allergen-induced murine model ofasthma[J].Respir Res,2007,8:90. 被引量:1
9Gervois P,Fruchart JC,Staels B.Drug insight:mechanisms of actionand therapeutic applications for agonists of peroxisome proliferator-activated receptors[J].Nutr Clin Pract,2007,3(2):145-156. 被引量:1
10Standiford TJ,Keshamouni VG,Reddy RC.Peroxisome proliferator-activated receptor-(gamma)as a regulator of lung inflammation andrepair[J].Proc Am Thorac Soc,2005,2(3):226-231. 被引量:1