摘要
目的了解神经外科不同种类、级别幕上胶质瘤术后早期癫痫发生率,探讨幕上胶质瘤手术后早期癫痫发作相关危险因素。方法回顾性分析四川大学华西医院神经外科2007年因幕上胶质瘤接受开颅手术且资料完整的患者258例的临床资料。结果本研究中术后早期癫痫(acute postoperative seizures,APOSs)发病率为4.3%(11/258),术前癫痫史、以癫痫为首发症状、术后颅内感染为术后早期癫痫易发因素(P<0.05)。结论颅脑手术后早期癫痫的发生影响患者康复及预后,针对癫痫发生易发因素的防治,有望减少手术后早期癫痫的发生。
Objective To explore the predisposing factors for acute postoperative seizures in patients with supratentorial gliomas. Methods A retrospective study was performed into complete files of 258 gliomas patients who had received craniotomies in year 2007 . Results In our study , the incidence of APOSs was 4.3% （ 11/258 ）, the risk factors included preoperative history of epilepsy, initial symptoms of epilepsy and intracranial infection postoperatively. Conclusion The acute postoperative seizures severely affected the healing and prognosis of patients,and rigorous prophylaxis and treatment targeting the risk factors may decrease the occurrence rate of postoperative seizures.
出处
《中国医学创新》
CAS
2010年第29期68-70,共3页
Medical Innovation of China
关键词
幕上胶质瘤
癫痫
手术后早期癫痫发作
相关因素
Supratentorial gliomas
Epilepsy
Acute postoperative seizures
Predisposing factors
