摘要
目的：采用大白鼠腹部岛状皮瓣为模型，研究β七叶皂甙钠对缺血／再灌流岛状皮瓣成活率的影响。方法：皮瓣缺血７小时３０分时经腹腔注射β－七叶皂甙钠（实验组）或同体积生理盐水（对照组），缺血８小时时恢复再灌流。术后第７天检测皮瓣成活率。结果β－七叶皂甙钠能使皮瓣成活率由对照组的２８．２６％提高到实验组的６３．４７％，差异有显著性。结论：β－七叶皂甙钠能提高缺血／再灌流岛状皮瓣的成活率。
objective: The effect of Sodium Aescinate on the survival of ischemia induced reperfusion injuried ventral island skin flap of rats was studied. Methods: Sodium Aescinate (experimental group) or normal saline (control group) was administered by intraperitoneal injection 7 hours after ischemia. The flaps were subjected to 8 hours of ischemia. Skin flap survival rtes were obtained 7 days postoperatively. Results: The result showed that Sodium Aescinate could increase flap survival rates from 28.26% of control group to 63.47% of experimental group, the differences was significant. Conclusions: This revealed that Sodium Aescinate could increase survival of ischemia induced reperfusion injuried ventral island skin flao.
出处
《口腔医学纵横》
CSCD
1999年第2期85-86,共2页
Journal of Comprehensive Stomatology
