期刊文献+

肠道间质瘤误诊为卵巢癌三例分析 被引量:3

Three cases of intestinal stromal tumor diagnosed as ovarian canser
下载PDF
导出
摘要 目的探讨临床上肠道间质瘤患者常常误诊为卵巢癌的原因,进一步明确他们之间的鉴别点,降低该病的临床误诊率。方法回顾性分析2007年3月至2010年4月在我院妇科住院的3例术前诊断为卵巢癌,术中探查及术后病理证实为肠道间质瘤患者的临床资料。结果 3例患者中2例为绝经后妇女,2例以急腹症表现入院,1例伴肿瘤标记物升高,仅1例术前行盆腔CT检查,结果提示肿瘤可能来源于卵巢或肠道。3例患者术前诊断均为卵巢癌,行开腹手术,术中探查结合术后病理诊断为肠道间质瘤。结论尤其是绝经后妇女出现盆腹腔肿物时应考虑到有肠道间质瘤的可能。血清CA125、超声联合盆腹腔CT检查有助于术前诊断。最终诊断依赖病理免疫组化证实。 Objective To explore causes that the clinical patients with intestinal stromal tumors are often misdiagnosed as ovarian cancer, further more,we can clarify the differential points between them to reduce the rate of misdiagnosis of the disease. Methods retrospective analysing three oases who are diagonosed ovarian cancer before surgery, from March 2007 to July 2010 in our gynecolngical hospital.They are confitreed as patients with intestinal stromal tumor from exploration and intranperative pathology .Results Two patients were postmenopeusal women, Two of them had acute abdomen symptoms.one of them had high tumor markers, only one case had done CT scanning, The results suggestted that tumors may be derived from the ovary or bowel Road. Three patients had been diagnosed as ovarian cancer before the operation and was found to be a intestinal stremal tumor during the operation. Conclusions When a big mass occurred in the pelvic of the women or postmenopausal women, it may be intestinal stromal tumor not from the ovary. Serum CA125, ultrasound and abdominal CT scanning can be helpful for the diagnosis before the surgery.The final diagnosia depended on immunohistochemistry.
出处 《遵义医学院学报》 2010年第4期354-357,共4页 Journal of Zunyi Medical University
关键词 腑道间质瘤 卵巢癌 急腹痘 Intestinal stromal tumor Ovarian censer Abdomen acute
  • 相关文献

参考文献10

  • 1MiettinenM,Bcay J-Y, Sobin LH,Mesenchymal tumors of the stomach,WHO classification of tumors.Pathology and genetics of tumors of digestive system[M]. Lyon:IARC Press,2000,62-65. 被引量:1
  • 2Blanchard DK,Bubbe JM,Metz CE,et al. Tumors of the small intestine [J].World J Surg,2000,24(4):421-442. 被引量:1
  • 3武爱文,季加孚,王培林,赵卫兵,李燕宁.胃和小肠间质瘤的预后因素分析[J].中国实用外科杂志,2006,26(8):607-609. 被引量:13
  • 4Connolly EM,Gaffney E,Reynolds JV. Gastrointestinal stromal tumors[J].Brl Surg,2003,90:1178-1186. 被引量:1
  • 5Tyronne I Goonewardene, Marcia R Hall,Management of a symptomatic patients on follow - up for ovarian cancer with rising CA-125 concentration [J]. The Lancet On cology, 2007,8 (9) : 813. 被引量:1
  • 6Markmann S, Gerber B,Briese V,Prognostic value of CA125 levels During primary therapy[J].Anticancer Res, 2007, 27 (4) : 1837. 被引量:1
  • 7Matteo D,Dandolu V,Lembert L, et al.Unusually large extra intestinal GIST presenting an abdomino-pelvic tumor[J].Arch Gynecol Obstet,2008,278:89-92. 被引量:1
  • 8Guerriero S,Ajossa S,Garau N,et al.Ultrasonography and color Doppler-based triage for adnexal masses to provide the most appropriate surgical approach [J]. Am J Obstet Gynecol,2005, 192:401-406. 被引量:1
  • 9Miettinen M,Sobin LH,Sarlomo Rikala M,et al. Immunohistochemical spectrum of gastrointesinal stromal tumors at different sites and their differential diagnosis with other tumors with a special reference to CD117(KIT) [J]. Mod Pathol,2000,13:1134-1142. 被引量:1
  • 10Kindblom LG,Remotti HE,Aldenborg F,et al.Gastronitestinal pace maker cell tumor : gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal [J ] . Am J Pathol,1998,152:1259-1269. 被引量:1

二级参考文献11

  • 1Miettinen M,Majidi M,Lasota J.Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs):a review[J].Eur J Cancer,2002,38 (Suppl 5):39-51. 被引量:1
  • 2Miettinen M,Lasota J.Gastrointestinal stromal tumors (GISTs):definition,occurrence,pathology,differential diagnosis and molecular genetics[J].Pol J Pathol,2003,54(1):3-24. 被引量:1
  • 3Fletcher CD,Berman JJ,Corless C,et al.Diagnosis of gastrointestinal stromal tumors:A consensus approach[J].Hum Pathol,2002,33(5):459-465. 被引量:1
  • 4Miettinen M,El-Rifai W,L HLS,et al.Evaluation of malignancy and prognosis of gastrointestinal stromal tumors:a review[J].Hum Pathol,2002,33(5):478-483. 被引量:1
  • 5Heinrich MC,Rubin BP,Longley BJ,et al.Biology and genetic aspects of gastrointestinal stromal tumors:KIT activation and cytogenetic alterations[J].Hum Pathol,2002,33(5):484-495. 被引量:1
  • 6Nilsson B,Bumming P,Meis-Kindblom JM,et al.Gastrointestinal stromal tumors:the incidence,prevalence,clinical course,and prognostication in the preimatinib mesylate era-a population based study in western Sweden[J].Cancer,2005,103(4):821-829. 被引量:1
  • 7Wardelmann E,Hrychyk A,Merkelbach-Bruse S,et al.Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors[J].J Mol Diagn,2004,6(3):197-204. 被引量:1
  • 8Schneider-Stock R,Boltze C,Lasota J,et al.Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors:a tissue microarray study[J].Clin Cancer Res,2005,11(2 Pt 1):638-645. 被引量:1
  • 9Nishitani A,Hirota S,Nishida T,et al.Differential expression of connexin 43 in gastrointestinal stromal tumours of gastric and small intestinal origin[J].J Pathol,2005,206(4):377-382. 被引量:1
  • 10DeMatteo RP LJ,Leung D,Mudan SS,et al.Two hundred gastrointestinal stromal tumors.Recurrence patterns and prognostic factors for survival[J].Ann Surg,2000,231(1):51-58. 被引量:1

共引文献12

同被引文献56

引证文献3

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部