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舒芬太尼对老年手术患者应激反应的影响 被引量:3

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摘要 手术创伤可引起代谢紊乱、血压波动及儿茶酚胺、皮质醇等应激激素的释放,这种变化对老年患者具有很大的潜在危险,可使心肌缺血或高血压患者的病情加重。研究表明,芬太尼可抑制应激反应,但剂量过大可产生呼吸抑制等不良反应。舒芬太尼是芬太尼的N-噻吩基衍生物,其镇痛效应为芬太尼的5~10倍,且具有起效快及无组胺释放等特点。
出处 《中国药物与临床》 CAS 2010年第11期1278-1279,共2页 Chinese Remedies & Clinics
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